Skip to Content
Merck

N3398

S-Nitroso-N-acetyl-DL-penicillamine

≥97%, Nitric oxide donor, powder

Synonym(s):

N-Acetyl-3-(nitrosothio)-DL-valine, S-Nitroso-N-acetylpenicillamine, SNAP

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C7H12N2O4S
CAS Number:
67776-06-1
Molecular Weight:
220.25
UNSPSC Code:
12352116
PubChem Substance ID:
24278584
NACRES:
NA.32
MDL number:
MFCD00272624

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

S-Nitroso-N-acetyl-DL-penicillamine, ≥97%, powder

SMILES string

CC(=O)NC(C(O)=O)C(C)(C)SN=O

InChI

1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)

InChI key

ZIIQCSMRQKCOCT-UHFFFAOYSA-N

assay

≥97%

form

powder

color

faint green to very dark green

solubility

H2O: ≥2 mg/mL, DMSO: ≥20 mg/mL, clear (faint green to very dark green)

storage temp.

−20°C

Quality Level

300

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

S-Nitroso-N-acetyl-DL-penicillamine (SNAP) has been used:
  • as a positive control in nitrite generation assay.
  • to block the activity of endogenous transglutaminase (TG2).
  • in proliferation assays to generate nitric oxide (NO) in cell cultures.

Biochem/physiol Actions

NO donor; vasodilator, smooth muscle relaxant, lymphocyte activator. Activates soluble guanylyl cyclase.
SNAP, a nitrosothiol derivative, releases nitric oxide (NO.) under physiological conditions thus making it a useful tool for studying pharmacological and physiological actions of NO. Because of its NO releasing properties SNAP is a potent vasodilator in vitro and in vivo and is less prone to produce pharmacological tolerance.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Muta. 2 - Skin Irrit. 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

N3398-25MG: + N3398-BULK: + N3398-VAR: + N3398-50MG: + N3398-50MG-PW: + N3398-25MG-PW:

jan

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
069M41111V
13180904
029M4094V
018M4085V
13170811

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Zorana Milanović et al.
Journal of veterinary internal medicine, 33(4), 1686-1694 (2019-06-09)
Babesia canis infection induces a marked acute phase response (APR) that might be associated with alteration in lipid and lipoprotein metabolism and disease prognosis. Dogs with B. canis-induced APR develop dyslipidemia with altered lipoprotein concentration and morphology. Twenty-nine client-owned dogs
Akshata R Naik et al.
The journal of physical chemistry. B, 123(32), 6997-7005 (2019-07-20)
The cell plasma membrane is a highly dynamic organelle governing a wide range of cellular activities including ion transport, secretion, cell division, growth, and development. The fundamental process involved in the addition of new membranes to pre-existing plasma membranes, however
Sophiya Garasia et al.
Scientific reports, 7(1), 1629-1629 (2017-05-11)
We assessed the association between depression status and prevalent and incident type 2 diabetes (T2D) as well as the interaction between depression and a genetic risk score (GS) based on 20 T2D single-nucleotide polymorphisms (SNPs) in a multi-ethnic longitudinal study.
Immunomodulatory activities of chitin microparticles on Leishmania major-infected murine macrophages.
Dehghani F
Archives of Medical Research, 42(7), 572-576 (2011)
Jodie D Anderson et al.
Journal of veterinary internal medicine, 33(4), 1593-1601 (2019-05-28)
Intravenous continuous rate infusion (IVCRI) of lispro at a starting dose of 0.09 U/kg/h and the use of 0.9% sodium chloride (NaCl) for fluid resuscitation in cats with diabetic ketoacidosis (DKA) have not been reported. Protocols for correction of electrolyte deficiencies
View All Related Papers

Articles

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

Related Content

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service