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Merck

R9629

D-(−)-Ribose

suitable for cell culture, BioReagent

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About This Item

Empirical Formula (Hill Notation):
C5H10O5
CAS Number:
50-69-1
Molecular Weight:
150.13
UNSPSC Code:
12352201
NACRES:
NA.75
PubChem Substance ID:
24899416
EC Number:
200-059-4
Beilstein/REAXYS Number:
1723081
MDL number:
MFCD00135453

Key Documents

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biological source

microbial

Quality Level

200

product line

BioReagent

assay

≥99% (GC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

88-92 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

OC[C@@H](O)[C@@H](O)[C@@H](O)C([H])=O

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

InChI key

PYMYPHUHKUWMLA-LMVFSUKVSA-N

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Application

D-(−)-Ribose has been used for microtissue fabrication and in cell culture.
This D-ribose has been qualified for use as a supplement in cell culture.

Biochem/physiol Actions

Ribose is an aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. Ribose-5-phosphate supports the biosynthesis of tryptophan and histidine and is a component of the pentose phosphate pathway.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

R9629-VAR: + R9629-BULK: + R9629-5G: + R9629-100G: + R9629-25G:

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Certificates of Analysis (COA)

Lot/Batch Number
028K0678
078K0668
028K06781
127K0697
107K0719

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Pedro Vizán et al.
International journal of cancer, 124(12), 2789-2796 (2009-03-03)
Cell cycle regulation is dependent on multiple cellular and molecular events. Cell proliferation requires metabolic sources for the duplication of DNA and cell size. However, nucleotide reservoirs are not sufficient to support cell duplication and, therefore, biosynthetic pathways should be
Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle
West AR, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 304(1), 4-16 (2012)
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Mohan AS, et al.
bioRxiv (2018)
Growth and host interaction of mouse segmented filamentous bacteria in vitro
Schnupf P, et al.
Nature, 520(7545), 99-100 (2015)
Matthew Walker et al.
Scientific reports, 10(1), 7696-7696 (2020-05-08)
When stretched, cells cultured on 2D substrates share a universal softening and fluidization response that arises from poorly understood remodeling of well-conserved cytoskeletal elements. It is known, however, that the structure and distribution of the cytoskeleton is profoundly influenced by
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