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Merck

SAB4700767

Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

clone HB5, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Hbsag Antibody, Hbsag Antibody - Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
HB5, monoclonal
Application:
ELISA
immunocytochemistry
Species reactivity:
hepatitis B virus
Citations:
5
Technique(s):
ELISA: suitable
immunocytochemistry: suitable

Key Documents

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Product Name

Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse, clone HB5, purified immunoglobulin, buffered aqueous solution

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

HB5, monoclonal

form

buffered aqueous solution

species reactivity

hepatitis B virus

concentration

1 mg/mL

technique(s)

ELISA: suitable
immunocytochemistry: suitable

isotype

IgG2a

shipped in

wet ice

storage temp.

2-8°C

Quality Level

100

Application

Monoclonal Anti-HBV antigen HBsAg antibody has been used in quantitative assays.

Biochem/physiol Actions

HBsAg acts as a clinical marker and helps to specify acute or chronic infection. Presence of HBsAg indicates HBV infection. Overexpression of HBsAg is seen in infected hepatocytes.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

HBsAg is the surface antigen of HBV (hepatitis B virus). It is secreted in the form of pleomorphic particles, mostly spherical and partly filamentous. HBV is usually spread due to percutaneous or mucosal exposure to infected blood and other body fluids.
The antibody HB5 recognizes following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Hepatitis B surface antigen (HBsAg) is a marker of infectivity.
Specificity of the antibody HB5 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB5 does not cross-block with the antibody HB3.

Immunogen

Purified HbsAg from human plasma.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

SAB4700767-100UG:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
532899
522471
513826

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Hepatitis B and D Protocols (2004)
Palashpriya Das et al.
World journal of hepatology, 12(10), 775-791 (2020-11-18)
The recent rise in the incidence of hepatitis B virus (HBV) infections in a densely populated city of eastern India ("mixing vessel" of people of varied socio-economic and immune status) prompted this study. Applying saliva on fingers for enumerating bank
Establishment of magnetic microparticles-assisted time-resolved fluoroimmunoassay for determinating biomarker models in human serum.
Ren ZQ, et al.
PLoS ONE, 10(6), e0130481-e0130481 (2015)
Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity.
Ott JJ, et al.
Vaccine, 30(12), 2212-2219 (2012)
Zhi-Qi Ren et al.
PloS one, 10(6), e0130481-e0130481 (2015-06-24)
In order to early screen and detect suspected biomarkers from pathogens and the human body itself, tracers or reaction strategies that can act as signal enhancers have been proposed forth at purpose. In this paper, we discussed the applicability of

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