Skip to Content

Key Documents

View All Documentation

SML1552

Tipiracil hydrochloride

≥98% (HPLC), thymidine phosphorylase inhibitor, powder

Synonym(s):

5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride, TPI hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C9H11ClN4O2 · HCl
CAS Number:
183204-72-0
Molecular Weight:
279.12
UNSPSC Code:
12352200
PubChem Substance ID:
329825960
NACRES:
NA.77
MDL number:
MFCD01571384
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Tipiracil hydrochloride, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[H]Cl.ClC1=C(CN2C(CCC2)=N)NC(NC1=O)=O

InChI

1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H

InChI key

KGHYQYACJRXCAT-UHFFFAOYSA-N

Gene Information

human ... TYMP(1890)

Biochem/physiol Actions

Tipiracil is an inhibitor of thymidine phosphorylase.
Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

SML1552-VAR: + SML1552-BULK: + SML1552-10MG: + SML1552-50MG:

jan

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library