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SRP3246

IP-10 from rat

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

Synonym(s):

CXCL10, crg-2, g-Interferon Inducible Protein 10

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Form:
lyophilized
Assay:
≥98% (HPLC), ≥98% (SDS-PAGE)
Biological source:
rat
Recombinant:
expressed in E. coli
Mol wt:
8.6 kDa

Key Documents

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biological source

rat

recombinant

expressed in E. coli

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

form

lyophilized

mol wt

8.6 kDa

packaging

pkg of 25 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.2 EU/μg endotoxin, tested

color

off-white to yellow

UniProt accession no.

P48973

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... CXCL10(245920)

Biochem/physiol Actions

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. Recombinant rat IP-10 is an 8.6 kDa protein containing 77 amino acid residues, including the four conserved cysteine residues present in CXC chemokines.

General description

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6 kDa protein containing 77 amino acid residues, including the four conserved cysteine residues present in CXC chemokines.

Other Notes

IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP

Physical form

Lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Storage Class

11 - Combustible Solids

wgk

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

SRP3246-25UG:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
0608449

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Malefyt, R.
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