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SRP3253

SDF-1 beta from rat

≥95%(SDS-PAGE & HPLC), recombinant, expressed in E. coli, lyophilized, suitable for cell culture

Synonym(s):

CXCL12, PBSF, Stromal-Cell Derived Factor-1

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
Biological source:
rat
Recombinant:
expressed in E. coli
Assay:
≥95% (HPLC), ≥95% (SDS-PAGE)
Form:
lyophilized
Mol wt:
8.4 kDa
Impurities:
<0.1 EU/μg endotoxin, tested
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Product Name

SDF-1 beta from rat, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

biological source

rat

recombinant

expressed in E. coli

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

form

lyophilized

potency

100.0-200.0 ng/mL

mol wt

8.4 kDa

packaging

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

color

yellow-white

UniProt accession no.

Q9QZD1

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... CXCL12(24772)

General description

SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1b is an 8.4 kDa protein containing 72 amino acid residues.

Biochem/physiol Actions

SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. Recombinant rat SDF-1b is an 8.4 kDa protein containing 72 amino acid residues.

Physical form

Lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Other Notes

KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

SRP3253-10UG:

jan

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Articles

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

M D'Apuzzo et al.
European journal of immunology, 27(7), 1788-1793 (1997-07-01)
In the bone marrow, progenitor (pro-) and precursor (pre-) B cells depend on close contact with stromal cells for growth and maturation. Stromal cell-derived factor 1 (SDF-1), also known as pre-B cell growth-stimulating factor, is produced by bone marrow stromal
E Oberlin et al.
Nature, 382(6594), 833-835 (1996-08-29)
A putative chemokine receptor that we previously cloned and termed LESTR has recently been shown to function as a co-receptor (termed fusin) for lymphocyte-tropic HIV-1 strains. Cells expressing CD4 became permissive to infection with T-cell-line-adapted HIV-1 strains of the syncytium-inducing