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Merck

1524806

USP

Phenol

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Hydroxybenzene

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About This Item

Linear Formula:
C6H5OH
CAS Number:
108-95-2
Molecular Weight:
94.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750800
MDL number:
MFCD00002143
Beilstein/REAXYS Number:
969616

Key Documents

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vapor pressure

0.36 mmHg ( 20 °C), 0.09 psi ( 55 °C)

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

SMILES string

Oc1ccccc1

InChI key

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

grade

pharmaceutical primary standard

vapor density

3.24 (vs air)

API family

salicylic acid, guaiacol, hexylresorcinol

autoignition temp.

1319 °F

expl. lim.

8.6 %

manufacturer/tradename

USP

density

1.071 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

Phenol, aromatic alcohol, is extensively employed in various industrial processes, consumer products, and pharmaceutical applications.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Camphorated Phenol Topical Gel
  • Camphorated Phenol Topical Solution
  • Sodium Salicylate
  • Salicylic Acid
  • Magnesium Salicylate
  • Metacresol
  • Chloroquine Phosphate

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

target_organs

Nervous system,Kidney,Liver,Skin

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 2

flash_point_f

177.8 °F - closed cup

flash_point_c

81 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Class I Designated Chemical Substances

prtr

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

1524806-500MG:4548173964638

jan

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ZnO nanoparticles-Synthesis, characterization and its application for phenol removal from synthetic and pharmaceutical industry wastewater
Sridar R, et al.
Environmental Nanotechnology, Monitoring & Management, 10(1), 388-393 (2018)
Phenol
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(5)(1), 3501-3501 (2013)
Rita A Busuttil et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(10), 2761-2772 (2014-03-25)
Gene-expression profiling has revolutionized the way we think about cancer and confers the ability to observe the synchronous expression of thousands of genes. The use of putative genome-level expression profiles has allowed biologists to observe the complex interactions of genes
Benjamin Vandendriessche et al.
Critical care medicine, 42(8), e560-e569 (2014-04-11)
Early detection and start of appropriate treatment are highly correlated with survival of sepsis and septic shock, but the currently available predictive tools are not sensitive enough to identify patients at risk. Linear (time and frequency domain) and nonlinear (unifractal
Yukari Yamane-Sando et al.
MicrobiologyOpen, 3(2), 196-212 (2014-02-11)
Sphingolipids are a family of eukaryotic lipids biosynthesized from sphingoid long-chain bases (LCBs). Sphingolipids are an essential class of lipids, as their depletion results in cell death. However, acute LCB supplementation is also toxic; thus, proper cellular LCB levels should
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Chloroquine Phosphate HPLC Assay & Impurity Profiling

Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

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