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Merck

1643361

USP

Taurine

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-Aminoethanesulfonic acid

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About This Item

Linear Formula:
NH2CH2CH2SO3H
CAS Number:
107-35-7
Molecular Weight:
125.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751225
MDL number:
MFCD00008197
Beilstein/REAXYS Number:
1751215

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InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

SMILES string

NCCS(O)(=O)=O

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

taurine

manufacturer/tradename

USP

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Taurine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors.
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

1643361-100MG:

jan

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Cory J Knoot et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(2), 388-393 (2014-12-31)
Intradiol aromatic ring-cleaving dioxygenases use an active site, nonheme Fe(3+) to activate O2 and catecholic substrates for reaction. The inability of Fe(3+) to directly bind O2 presents a mechanistic conundrum. The reaction mechanism of protocatechuate 3,4-dioxygenase is investigated here using
Allan D Rasmussen et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 67(1), 13-20 (2014-12-03)
The overall purpose of this study was to establish a model that may be used for examining the effect of Vigabatrin-induced retinal toxicity in pigmented rats, and subsequently examine the possible effects of taurine on the retinal toxicity. In the
Shen Luo et al.
Free radical biology & medicine, 75, 84-94 (2014-07-25)
Cofilin regulates reorganization of actin filaments (F-actin) in eukaryotes. A recent finding has demonstrated that oxidation of cofilin by taurine chloramine (TnCl), a physiological oxidant derived from neutrophils, causes cofilin to translocate to the mitochondria inducing apoptosis (F. Klamt et
María V Correa et al.
Pflugers Archiv : European journal of physiology, 466(9), 1819-1830 (2013-12-12)
Emerging evidence supports a key role for endothelin-1 (ET-1) and the transactivation of the epidermal growth factor receptor (EGFR) in angiotensin II (Ang II) action. We aim to determine the potential role played by endogenous ET-1, EGFR transactivation and redox-dependent
Atsushi Kuwahara et al.
Nature communications, 6, 6286-6286 (2015-02-20)
In the developing neural retina (NR), multipotent stem cells within the ciliary margin (CM) contribute to de novo retinal tissue growth. We recently reported the ability of human embryonic stem cells (hESCs) to self-organize stratified NR using a three-dimensional culture
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