479306
cis-ジアンミン白金(II)ジクロリド
≥99.9% trace metals basis
別名:
cis-ジアンミン白金(II) ジクロリド, cis-ジクロロジアンミン 白金(II), cis-白金(II) ジアンミンジクロリド, シスプラチン
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この商品について
化学式:
Pt(NH3)2Cl2
CAS番号:
分子量:
300.05
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
EC Number:
239-733-8
MDL number:
製品名
cis-ジアンミン白金(II)ジクロリド, ≥99.9% trace metals basis
InChI key
LXZZYRPGZAFOLE-UHFFFAOYSA-L
InChI
1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
SMILES string
N.N.Cl[Pt]Cl
assay
≥99.9% trace metals basis
reaction suitability
core: platinum
reagent type: catalyst
mp
270 °C (lit.)
antibiotic activity spectrum
neoplastics
mode of action
DNA synthesis | interferes
Quality Level
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Application
cis-ジアンミン白金(II)ジクロリドは、種々の薬物担体の薬物送達における効率を試験するモデル薬物として使用されます。
精巣癌の進行抑制に用いられる有効性の高い化学療法薬
Biochem/physiol Actions
強力な抗悪性腫瘍プラチナ製剤です。DNAジヌクレオチドd(pGpG)との間に細胞毒性付加体を形成し、鎖内架橋を誘導します。
signalword
Danger
Hazard Classifications
Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
保管分類
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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