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Merck

48640

没食子酸エチル

antioxidant, ≥96.0% (HPLC)

別名:

3,4,5-Trihydroxybenzoic acid ethyl ester, Ethyl 3,4,5-trihydroxybenzoate, Progallin A

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この商品について

化学式:
3,4,5-(OH)3C6H2COOC2H5
CAS番号:
分子量:
198.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-608-5
Beilstein/REAXYS Number:
2116014
MDL number:
Assay:
≥96.0% (HPLC)
Form:
solid
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Quality Level

assay

≥96.0% (HPLC)

form

solid

functional group

ester

SMILES string

CCOC(=O)c1cc(O)c(O)c(O)c1

InChI

1S/C9H10O5/c1-2-14-9(13)5-3-6(10)8(12)7(11)4-5/h3-4,10-12H,2H2,1H3

InChI key

VFPFQHQNJCMNBZ-UHFFFAOYSA-N

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General description

Ethyl gallate is the ethyl ester of gallic acid that belongs to a class of phenolic compound. It is an aromatic compound that is commonly used as a starting material during the synthesis of ellagic acid via transesterification reactions.

Application

  • Wound healing enhancement: Ethyl gallate, isolated from Caesalpinia mimosoides, demonstrated significant effects in promoting cutaneous wound healing. This discovery supports its potential application in therapeutic treatments for skin regeneration (Bhat et al., 2023).
  • Pharmacokinetics in ethanolic extracts: A study involving ethanolic extracts of Terminalia chebula, which include ethyl gallate, detailed the pharmacokinetics of these active compounds in rats, providing critical data for pharmaceutical applications and drug development processes (Yao et al., 2023).
  • Ethnopharmacology research: Research on Rubus idaeus, a source of ethyl gallate, covered extensive ethnobotany, phytochemical, and pharmacological aspects, offering insights into traditional uses and modern applications, highlighting its potential in ethnopharmacology (Tao et al., 2023).
  • Dermal applications: Ethyl gallate was used in a topical ointment from Caesalpinia mimosoides to attenuate dermal wounds. This application underscores its effectiveness in skin care and treatment strategies (Bhat et al., 2022).
  • Neuroprotective effects: The Jingchuan tablet, which includes ethyl gallate, has been studied for its therapeutic role in treating ischaemic cerebral stroke, focusing on the HIF-1α/EPO/VEGFA signalling pathway. This research outlines its importance in neuroprotective strategies (Zhang et al., 2022).
Ethyl gallate is utilized as a reactant in thesynthesis of quinoxalines via sustainable green chemistry process.

保管分類

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

48640-VAR-F: + 48640-500G-F: + 48640-100G-F: + 48640-BULK-F:

jan


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試験成績書(COA)

Lot/Batch Number

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Tomoya Takahashi et al.
PloS one, 13(10), e0204856-e0204856 (2018-10-12)
Catechins, biologically active polyphenols in green tea, exhibit various biological activities, such as anticancer and antiviral activities, arising from interactions with functional proteins. However, the molecular details of these interactions remain unclear. In this study, we investigated the interactions between
Xiaobo Wang et al.
Journal of ethnopharmacology, 241, 111801-111801 (2019-03-18)
Rhodiola crenulata, a traditional Tibetan medicine, has shown promise in the treatment of hypobaric hypoxia (HH)-induced brain injury. However, the underlying mechanisms remain unclear. This study investigated the protective effects of R. crenulata aqueous extract (RCAE) on HH-induced brain injury
Steven N Mink et al.
Journal of applied physiology (Bethesda, Md. : 1985), 110(2), 359-374 (2010-11-13)
Although hydrogen peroxide (H2O2) is a well-described reactive oxygen species that is known for its cytotoxic effects and associated tissue injury, H2O2 has recently been established as an important signaling molecule. We previously demonstrated that lysozyme (Lzm-S), a mediator of
C Cueva et al.
Letters in applied microbiology, 54(6), 557-563 (2012-03-28)
To investigate the effect of seven wine phenolic compounds and six oenological phenolic extracts on the growth of pathogenic bacteria associated with respiratory diseases (Pseudomonas aeruginosa, Staphylococcus aureus, Moraxella catarrhalis, Enterococcus faecalis, Streptococcus sp Group F, Streptococcus agalactiae and Streptococcus
J Wu et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 76(4), 661-664 (1999-04-01)
The peroxidation of human erythrocytes induced by peroxyl radical initiator and its inhibition by several gallate esters (e.g., propyl, methyl, ethyl) and Trolox (a more polar analogue of vitamin E) have been studied. The antioxidant activity was determined on erythrocytes

プロトコル

HPLC Analysis of Polyphenols in Nero d'Avola Red Wine on Discovery® HS C18 (UV 280 nm)

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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