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この商品について
化学式:
[Ca5(OH)(PO4)3]x
CAS番号:
分子量:
502.31
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Form:
dispersion
nanoparticles
nanoparticles
製品名
ヒドロキシアパタイト, nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)
Quality Level
InChI
1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10
SMILES string
[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O
InChI key
XYJRXVWERLGGKC-UHFFFAOYSA-D
form
dispersion
nanoparticles
contains
≤0.025 wt. % dispersant (non-metal based)
concentration
10 wt. % in H2O
surface area
14.3 m2/g , typical
particle size
<200 nm (BET)
pH
4-6
density
1.038 g/mL at 25 °C
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関連するカテゴリー
Application
ハイドロキシアパタイトは、以下の用途に使用されています:
- 骨の無機成分と化学的に類似していることおよび骨誘導特性を有することから、 骨代替品のインプラント材料。
- カプセル化能といくつかの薬物およびタンパク質に対する親和性があるため、遺伝子および 薬物送達用の媒体。
- pH応答性粒子状乳化剤。
Features and Benefits
- 生体適合性
- 骨伝導性
- 生理学的条件下で 安定
- 高い機械的強度
General description
ハイドロキシアパタイト(HAP)は生体組織と直接結合できる特徴を持つ骨伝導性生体セラミックです。ゾル-ゲル法、水熱法、多重エマルジョン法、生体模倣析出法、電着法などさまざまな手法で容易に調製できます。
Legal Information
Engi-Mat社製
保管分類
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Liam M Grover et al.
Biomaterials, 34(28), 6631-6637 (2013-06-12)
Pyrophosphate ions are both inhibitors of HA formation and substrates for phosphatase enzymes. Unlike polyphosphates their hydrolysis results simultaneously in the complete loss of mineral formation inhibition and a localised elevation in orthophosphate ion concentration. Despite recent advances in our
W Zhang et al.
Journal of dental research, 92(12), 1136-1141 (2013-10-08)
Stem cell-based bone tissue engineering has been recognized as a new strategy for maxillary sinus floor elevation. More rapid bone formation may enhance this technique when simultaneous dental implant placement is desired. Adipose tissue-derived stem cells (ADSCs) and bone marrow
Satyavrata Samavedi et al.
Acta biomaterialia, 9(9), 8037-8045 (2013-06-25)
Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the regeneration of bone tissue because of their ability to induce osteoblastic differentiation in progenitor cells. Despite the progress made towards fabricating CPCs possessing a range of surface features
Xi Chen et al.
The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)
Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly
Thomas Lyon et al.
The Journal of bone and joint surgery. American volume, 95(23), 2088-2096 (2013-12-07)
Recombinant human bone morphogenetic protein-2 (rhBMP-2) applied on an absorbable collagen sponge improves open tibial fracture-healing as an adjunct to unreamed intramedullary nail fixation. We evaluated rhBMP-2 and a new, injectable calcium phosphate matrix (CPM) formulation in acute closed tibial
資料
Nanoparticles can be used for applications such as growing cells for tissue engineering, nanocomposites used in orthopedics, and miniaturized sensors for DNA, pathogens, and chemicals.
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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