900188
Poly(N-isopropyl acrylamide)
NHS ester end functionalized, average Mn 5,000
別名:
PNIPAM, polyNIPAM
Application
Poly(N-isopropyl acrylamide) (PolyNIPAM) is a stimuli-responsive polymer. This product features low polydispersity (PDI), which typically leads to better reproducibility in applications, and a terminal N-hydroxysuccinimide (NHS) functional group, allowing for rapid conjugation of biomolecules, small molecules, or other polymers. PolyNIPAM has been used in development of a variety of thermosensitive coated micro/nano materials, including thermoresponsive polymeric drug delivery systems.
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
900188-1G: + 900188-BULK: + 900188-VAR:
jan
Aniket S Wadajkar et al.
Acta biomaterialia, 8(8), 2996-3004 (2012-05-09)
New magnetic-based core-shell particles (MBCSPs) were developed to target skin cancer cells while delivering chemotherapeutic drugs in a controlled fashion. MBCSPs consist of a thermo-responsive shell of poly(N-isopropylacrylamide-acrylamide-allylamine) and a core of poly(lactic-co-glycolic acid) (PLGA) embedded with magnetite nanoparticles. To
Chenglin Yi et al.
Journal of colloid and interface science, 380(1), 90-98 (2012-05-29)
Self-assembled polymeric micelles can be used as efficient particulate emulsifiers. To explore the relationship between micellar structure and emulsification performance, pH- and temperature-responsive self-assembled micelles were prepared and used as emulsifiers, based on a novel grafted polymer poly(styrene-alt-maleic acid)-graft-poly(N-isopropyl acrylamide)
Manuel Pernia Leal et al.
ACS nano, 6(12), 10535-10545 (2012-11-03)
We report a procedure to grow thermo-responsive polymer shells at the surface of magnetic nanocarriers made of multiple iron oxide superparamagnetic nanoparticles embedded in poly(maleic anhydride-alt-1-ocatadecene) polymer nanobeads. Depending on the comonomers and on their relative composition, tunable phase transition
William S Turner et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 100(8), 2060-2072 (2012-08-14)
The packaging and delivery of cells for cardiac regeneration has been explored using a variety biomaterials and delivery methods, but these studies often ignore one or more important design factors critical for rebuilding cardiac tissue. These include the biomaterial architecture
Yan Xia et al.
Chemical communications (Cambridge, England), 49(25), 2566-2568 (2013-02-21)
Site-specific protein conjugates with RAFT polymers were synthesized using expressed protein ligation. Stable micelles were formed from both linear block copolymer and Y-shaped conjugates.
資料
ナノファイバーとスマートポリマーと組み合わせた「スマートナノファイバー」は外部刺激を与えることでその性質を劇的に遠隔制御が可能であるため、医療分野のみならず様々な分野で期待が寄せられています。薬剤放出の制御とハイパーサーミアへの応用について解説いただきました。
Professor Mitsuhiro Ebara provides insights on several types of smart nanofiber mesh systems that have been explored for different drug delivery purposes.
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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