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KITALYSIS-RCM

KitAlysis High-Throughput Medium (5, 6, 7) Ring Closing Metathesis Reaction Screening Kit - Pack of 2

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この商品について

NACRES:
NA.22
UNSPSC Code:
12161600
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product line

KitAlysis

reaction suitability

core: palladium, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling

storage temp.

2-8°C

Application

Screening kit for ring closing metathesis. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.

Step-by-Step Guide for Ring Closing Metathesis/Cross Metathesis Reaction Screening Kit

Downloadable experimental excel file

Each kit contains 2 customizable screening sets that include the following components:
  • 6x4 pre-weighed catalysts in glass microvials loaded with stir bars and topped with cap mat.
  • 2 (2 mL) ampules each of of ClPh, PhMe, i-PrOAc, Me-THF, and TFA.
  • 1 KitAlysis 24-well reaction block replacement film.
  • 4 empty substrate stock solution reaction vials with stir bars.
  • 1 internal standard.
Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reaction in parallel.
  • 20 μmol reactions with 1 μmol catalyst (5 mol%), 0.2 M concentration, and optional TFA additive.
  • Customizable and downloadable excel template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC


キットの構成要素のみ

製品番号
詳細

  • SnapIT Ampule Opener, Regular, for 1-2ml, 5-10ml, 10-15ml ampoules 1 EA

キットの構成要素は別途購入可能です。

製品番号
詳細
SDS & 価格

  • Grubbs Catalyst® M204, Umicore 3 µmol
    SDS

  • Hoveyda-Grubbs Catalyst® M720, Umicore, 97% 3 µmol
    SDS

  • Grubbs Catalyst® M102, Umicore, 97% 3 µmol
    SDS

  • Grubbs Catalyst® M207, Umicore 3 µmol
    SDS

  • Hoveyda-Grubbs Catalyst® M721, Umicore 3 µmol
    SDS

  • Hoveyda-Grubbs Catalyst® M722, Umicore 3 µmol
    SDS

  • Isopropyl acetate, anhydrous, ZerO2®, ≥99.6% 8 mL
    SDS

すべて表示 (11)

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

保管分類

3 - Flammable liquids

wgk

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Please refer to KIT Component information

pdsc

Please refer to KIT Component information

prtr

Please refer to KIT Component information

fsl

Please refer to KIT Component information

ishl_indicated

Please refer to KIT Component information

ishl_notified

Please refer to KIT Component information

cart

キットコンポーネントの情報を参照してください

jan



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試験成績書(COA)

Lot/Batch Number

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以前この製品を購入いただいたことがある場合

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プロトコル

Catalyst screening kits, KitAlysis™, and TLC-MS analysis enable high-throughput synthesis and analysis for efficient reactions.

資料

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

関連コンテンツ

有機合成における化学反応の設計および最適化の目標は、反応パラメータを正確にコントロールし、目的の分子に至る最適な反応経路を見つけることです。

The Olefin Application Metathesis Application Guide provides - The Key Features of Metathesis, General Reaction Procedures, Guidance for Choosing the Correct Metathesis Route, A Metathesis Quick Guide

Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.

すべての関連コンテンツを見る

High-Throughput Experimentation in Catalysis and Materials Science.
Gordillo A, et al.
Ullmann's Encyclopedia of Industrial Chemistry (2014)
Scientist-Led High-Throughput Experimentation (HTE) and Its Utility in Academia and Industry.
Schmink JR, et al.
Aldrichimica Acta, 46, 71-80 (2013)
Spencer D Dreher et al.
Journal of the American Chemical Society, 130(29), 9257-9259 (2008-06-28)
Microscale parallel experimentation was used to discover three catalyst systems capable of coupling secondary organotrifluoroborates with sterically and electronically demanding aryl chlorides and bromides. The ensuing results represent the first comprehensive study of alkylboron coupling to aryl chlorides and, in