製品名
16:0-18:2 PS, 1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (840060P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840060P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C40H74NO10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(43)51-36(34-49-52(46,47)50-35-37(41)40(44)45)33-48-38(42)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,36-37H,3-10,12,14-16,19-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/b13-11-,18-17-;/t36-,37+;/m1./s1
InChI key
WPLLCKLCLMRAPV-WHVRKWPVSA-M
General description
Phosphatidylserine (PS) is an acidic phospholipid, abundantly found in the protein myelin. It is localized to the membranes and present in plasma. PS constitutes 2% to 20% of the total phospholipid mass.
Application
16:0-18:2 PS or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine (sodium salt) might be used in the preparation of giant unilamellar liposomes (GULs).
Biochem/physiol Actions
Phosphatidylserine (PS) supports nerve cell membranes and myelin. It affects the catabolism and anabolism of neurotransmitters acetylcholine (ACh), norepinephrine, serotonin and dopamine.
Packaging
5 mL Clear Glass Sealed Ampule (840060P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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保管分類
11 - Combustible Solids
A Y Dunina-Barkovskaya et al.
The Journal of membrane biology, 198(2), 77-87 (2004-05-13)
Low gadolinium concentrations induce rapid gigaseal formation and cell adhesion to glass and plastic (polystyrene) substrates in the slime mutant of Neurospora crassa. Cellular adhesion is independent of an integrin-mediated mechanism, because pretreatment with the oligopeptide ARG-GLY-ASP-SER (RGDS) did not
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly