製品名
12:0-13:0 PI, Avanti Research™ - A Croda Brand LM1500, methanol solution
assay
>99% (TLC)
form
methanol solution
packaging
pkg of 1 × 1 mL (LM1500-1EA)
manufacturer/tradename
Avanti Research™ - A Croda Brand LM1500
concentration
~10 μg/mL (Refer to C of A for lot specific concentration. )
application(s)
lipidomics
metabolomics
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[NH4+]
InChI key
REGULBPHXGUPTE-RBKCQXOZSA-N
General description
ホスファチジルイノシトール（PI）は、動物の組織および細菌によくみられます。PIは、水およびクロロホルム／メタノールにやや溶けやすい性質があります。
Application
12:0-13:0 PIまたは1-ドデカノイル-2-トリデカノイル-sn-グリセロ-3-ホスホ-(1′-ミオ-イノシトール)は、エレクトロスプレーイオン化タンデム質量分析法（ESI-MS/MS）および液体クロマトグラフィー質量分析法（LC-MS）を用いた脂質の定量／分析の内部標準物質として使用されています。
Packaging
2 mL アンバーガラス密封アンプル（LM1500-1EA）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Disclaimer
Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
保管分類
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Penelope Dimas et al.
eLife, 8 (2019-05-08)
Oligodendrocytes (OLs) support neurons and signal transmission in the central nervous system (CNS) by enwrapping axons with myelin, a lipid-rich membrane structure. We addressed the significance of fatty acid (FA) synthesis in OLs by depleting FA synthase (FASN) from OL
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced
Milena Vukotic et al.
Molecular cell, 67(3), 471-483 (2017-07-18)
Mutations in mitochondrial acylglycerol kinase (AGK) cause Sengers syndrome, which is characterized by cataracts, hypertrophic cardiomyopathy, and skeletal myopathy. AGK generates phosphatidic acid and lysophosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor progression. However, the