05-672
Anti-dimethyl-Histone H4 (Lys20) Antibody, clone 6G7/H4
clone 6G7/H4, Upstate®, from mouse
別名:
H4K20me2, Histone H4 (di methyl K20)
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
6G7/H4, monoclonal
Species reactivity:
human, bovine, mouse, rat
Application:
IHC, IP, WB
Citations:
5
biological source
mouse
antibody product type
primary antibodies
clone
6G7/H4, monoclonal
species reactivity
human, bovine, mouse, rat
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
dimethylation (Lys20)
Quality Level
Gene Information
bovine ... H4C1(617905)
human ... H4C1(8359)
mouse ... H4C1(326619)
General description
10kDa
Immunogen
peptide corresponding to amino acids 17-28 of human histone H4 (RHRdimKVLRDNIQGC) dimethylated on lysine 20.
Application
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Use Anti-dimethyl-Histone H4 (Lys20) Antibody, clone 6G7/H4 (mouse monoclonal antibody) validated in IP, WB, IHC to detect dimethyl-Histone H4 (Lys20) also known as H4K20me2, Histone H4 (di methyl K20).
Biochem/physiol Actions
methyl-Histone H4
Physical form
Format: Purified
PBS
Protein G Chromatography
Preparation Note
2 years at -20°C
Analysis Note
routinely evaluated by immunoblot on HeLa acid extracts
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
05-672:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Kenichi Nishioka et al.
Molecular cell, 9(6), 1201-1213 (2002-06-28)
We have purified a human histone H4 lysine 20 methyltransferase and cloned the encoding gene, PR/SET07. A mutation in Drosophila pr-set7 is lethal: second instar larval death coincides with the loss of H4 lysine 20 methylation, indicating a fundamental role
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.
Frederick A Mallette,Francesca Mattiroli,Gaofeng Cui,Leah C Young,Michael J Hendzel et al.
The Embo Journal null
Ai-Shun Guo et al.
Molecular medicine reports, 14(5), 4613-4621 (2016-10-26)
The present study aimed to investigate the differential expression and clinical significance of histone methyltransferase G9a, histone H3K9me2 and histone H3K9me1 in human brain glioma and adjacent tissue samples. It also aimed to observe the effect and mechanism of BIX‑01294, as
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 05-672 | 04053252275807 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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