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1.07427

Propyl 4-hydroxybenzoate

Name: Propyl 4-hydroxybenzoate
Brand: MM

EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, NF

別名:

Propyl 4-hydroxybenzoate, Propylparaben

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この商品について

実験式（ヒル表記法）:

C₁₀H₁₂O₃

CAS番号:

94-13-3

分子量:

180.20

UNSPSC Code:

12352108

EC Index Number:

202-307-7

MDL number:

MFCD00002354

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特性

Quality Level

500

agency

ChP, JP, NF, BP, Ph. Eur.

vapor pressure

0.67 hPa ( 122 °C)

product line

EMPROVE^® EXPERT

form

solid

autoignition temp.

>600 °C

potency

>5000 mg/kg LD₅₀, oral (Rat)

technique(s)

API processing | cocrystal formation: suitable

pH

6-7 (20 °C in H₂O, saturated solution)

mp

96-98 °C

transition temp

flash point 180 °C

solubility

0.4 g/L

density

1.063 g/cm³ at 102 °C

application(s)

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

SMILES string

O(CCC)C(=O)c1ccc(cc1)O

InChI

1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3

InChI key

QELSKZZBTMNZEB-UHFFFAOYSA-N

詳細

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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hcodes

H412

pcodes

P273 - P501

Hazard Classifications

Aquatic Chronic 3

保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

356.0 °F

flash_point_c

180 °C

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Class II Designated Chemical Substances

prtr

試験成績書（COA）

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資料

Comparison of Preservatives Used in Various Therapeutic Applications

Find key considerations for the selection and use of benzalkonium chloride, benzyl alcohol, benzaldehyde, parabens, benzoic acid, and sodium benzoate as preservatives.

Criteria for Selecting Preservatives Used in Liquid Formulation

Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

グローバルトレードアイテム番号

カタログ番号	GTIN
1.07427.9029	04022536938714
1.07427.5000	04022536090658