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Merck

1.08262

トリフルオロ酢酸

for spectroscopy Uvasol®

別名:

TFA

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この商品について

化学式:
CF3COOH
CAS番号:
76-05-1
分子量:
114.02
UNSPSC Code:
12191502
NACRES:
NA.03
EC Index Number:
200-929-3
MDL number:
MFCD00004169
Beilstein/REAXYS Number:
742035

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製品名

トリフルオロ酢酸, for spectroscopy Uvasol®

InChI key

DTQVDTLACAAQTR-UHFFFAOYSA-N

SMILES string

OC(C(F)(F)F)=O

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

vapor density

3.9 (vs air)

vapor pressure

97.5 mmHg ( 20 °C)

Quality Level

200

product line

Uvasol®

assay

≥99.8% (acidimetric)

form

liquid

concentration

≥99.8%

technique(s)

UV/Vis spectroscopy: suitable

impurities

≤10% Water (Karl Fischer)

evapn. residue

≤0.005%

color

APHA: ≤10

transmittance

265 nm, ≥10.0%
305 nm, ≥50.0%
320 nm, ≥80.0%
325 nm, ≥90.0%

refractive index

n20/D 1.3 (lit.)

pH

1 (10 g/L in H2O)

bp

72.4 °C (lit.)

mp

−15.4 °C (lit.)

solubility

soluble 10 g/mL

density

1.489 g/mL at 20 °C (lit.)

storage temp.

2-30°C

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Analysis Note

Assay (acidimetric): ≥ 99.8 %
Water (K. F.): ≤ 0.10 %
Colour number (Apha): ≤ 10
Evaporation residue: ≤ 0.005 %
UV-transmission (at 265 nm): ≥ 10.0 %
UV-transmission (at 305 nm): ≥ 50.0 %
UV-transmission (at 320 nm): ≥ 80.0 %
UV-transmission (from 325 nm): ≥ 90.0 %

Application


  • Characterization of ribostamycin and its impurities using a nano-quantity analyte detector: This study examines ribostamycin and its impurities using a nano-quantity analyte detector and details a systematic comparison of three different aerosol detectors. The role of trifluoroacetic acid as a mobile phase additive enhances detection sensitivity and analytical precision, making it crucial for accurate impurity profiling and pharmaceutical quality control (Meng et al., 2024).

  • Paradigm Shift: Major Role of Ion-Pairing-Dependent Size Exclusion Effects in Bottom-Up Proteomics Reversed-Phase Peptide Separations: This research highlights the critical role of trifluoroacetic acid in modifying the ion-pairing and size exclusion properties of peptides during reversed-phase separations in proteomics. The study provides a deeper understanding of the mechanisms influencing peptide behavior, which is essential for developing more effective analytical techniques (Yeung et al., 2024).

  • New fabric phase sorptive extraction for nondestructive analysis of heritage textile samples: This paper introduces a novel fabric phase sorptive extraction method using trifluoroacetic acid among other solvents to analyze heritage textile samples nondestructively. This method demonstrates significant potential in cultural heritage preservation and forensic science by allowing detailed analysis without damaging the original artifacts (Tanasescu et al., 2024).

  • Preparation and characterization of stationary phase gradients on C8 liquid chromatography columns: The study discusses the preparation and characterization of stationary phase gradients for chromatography columns, with trifluoroacetic acid used to adjust the pH and ionic strength of the mobile phase. This modification is shown to enhance the chromatographic separation of complex mixtures, proving vital for analytical and preparative scale separations (Cecil et al., 2024).

  • Optimization of Cyanocobalamin (Vitamin B(12)) Sorption onto Mesoporous Superparamagnetic Iron Oxide Nanoparticles: This investigation utilizes trifluoroacetic acid in the synthesis and functionalization of nanoparticles for efficient vitamin B(12) sorption. The study explores the implications for targeted drug delivery systems and bioseparation, demonstrating the adaptability and effectiveness of these engineered nanoparticles (Flieger et al., 2024).

General description

Accurate analytic results in UV/VIS and infrared spectroscopy depend on the use of very pure solvents for sample preparation. The Uvasol<TMSYMBOL></TMSYMBOL> solvents range has been specially designed for spectroscopy and other applications requiring solvents of the highest spectral purity. The refinement process allows a greater degree of security in applications and avoids misinterpretation of analytical results caused by traces of UV, IR and fluorescence contamination. Uvasol<TMSYMBOL></TMSYMBOL> solvents offer best UV transmittance. In all specifications the minimum transmittance for 5 typical wavelengths are identified.

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

UVASOL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

保管分類

8A - Combustible, corrosive hazardous materials

wgk

WGK 2

flash_point_f

212.0 °F - Pensky-Martens closed cup

flash_point_c

> 100 °C - Pensky-Martens closed cup

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グローバルトレードアイテム番号

カタログ番号GTIN
1.08262.100004027269048921
1.08262.250004027269167028

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