1.41544
Parteck® MXP (Polyvinyl alcohol 3-82)
EMPROVE® ESSENTIAL, Ph. Eur.
別名:
Parteck® Polyvinyl alcohol, PVA, Polyvinyl alcohol
認証
Ph. Eur.
品質水準
製品種目
EMPROVE® ESSENTIAL
フォーム
powder
アプリケーション
pharmaceutical
solid formulation
solubility enhancement
保管温度
15-25°C
InChI
1S/C2H4O/c1-2-3/h2-3H,1H2
InChI Key
IMROMDMJAWUWLK-UHFFFAOYSA-N
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詳細
With a lower degree of hydrolysis along the PVA chain, Parteck® MXP 3-82 Polyvinyl alcohol is especially beneficial in forming strong interactions with hydrophobic drug molecules – in the solid state and in solution. Due to this, Parteck® MXP 3-82 excipient has very high capabilities as a precipitation inhibitor and can maintain high levels of supersaturation for physiologically relevant timescales. As a result, Parteck® MXP 3-82 Polyvinyl alcohol can provide solubility enhancement for even the most challenging molecules.
アプリケーション
Parteck® MXP 3-82 is a PVA-based excipient that is used in Hot Melt Extrusion for Solubility Enhancement in oral solid dosage forms.
特徴および利点
- Superior supersaturation performance via precipitation inhibition
- High thermostability up to 250°C, extending the potential application range
- Stable high drug loads and suitability with a broad range of APIs
- Flexible release kinetics
- Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing
- Optimized powder properties for excellent performance in the HME process
- Suitable polymer properties for HME, spray drying and 3D printing processes
法的情報
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類コード
11 - Combustible Solids
WGK
WGK 1
引火点(°F)
No data available
引火点(℃)
No data available
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 1.41544.1000 | 04065266953343 |
| 1.41544.9025 | 04065266953121 |