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Merck

1.59014

Acetonitrile solution

suitable for LC/MS, LiChrosolv®, contains 0.1% (v/v) trifluoroacetic acid

別名:

Acetonitrile solution, ACN, ACN + TFA, Cyanomethane, Ethyl nitrile, Methyl cyanide

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この商品について

化学式:
CH3CN
CAS番号:
分子量:
41.05
NACRES:
NA.03
UNSPSC Code:
41116004
MDL number:
Beilstein/REAXYS Number:
4124158
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製品名

アセトニトリル 溶液, hypergrade for LC-MS LiChrosolv®

InChI

1S/C2H3N/c1-2-3/h1H3

SMILES string

CC#N

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

vapor pressure

97 hPa ( 20 °C)

product line

LiChrosolv®

form

liquid

concentration

0.095-0.105 % (v/v)

technique(s)

HPLC: suitable
LC/MS: suitable

impurities

≤0.025 ppm K (Potassium)
≤0.05 ppm Al (Aluminium)
≤0.05 ppm Ca (Calcium)
≤0.05 ppm Fe (Iron)
≤0.05 ppm Mg (Magnesium)
≤0.25 ppm Na (Sodium)

color

APHA: ≤10

transition temp

flash point 2 °C

density

0.782 g/mL at 25 °C

format

mixture

storage temp.

2-30°C

Quality Level

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Analysis Note

Acid content: 0.095 - 0.105 % (v/v)
Identity: passes test
Color: ≤ 10 Hazen
Al (Aluminium): ≤ 0.05 ppm
Ca (Calcium): ≤ 0.05 ppm
Fe (Iron): ≤ 0.05 ppm
K (Potassium): ≤ 0.025 ppm
Mg (Magnesium): ≤ 0.05 ppm
Na (Sodium): ≤ 0.25 ppm
Gradient grade (at 210 nm): ≤ 1.0 mAU
Gradient grade (at 254 nm): ≤ 0.5 mAU
Suitable for LC-MS; Intensity of background mass peak based on reserpine(APCI/ESI positive): ≤ 2 ppb
Filtered by 0.2 µm filter.

Application


  • Retention time prediction for post-translationally modified peptides: Ser, Thr, Tyr-phosphorylation.: This study presents a methodology for predicting retention times of phosphorylated peptides using high-performance liquid chromatography (HPLC) (Battellino et al., 2024).

  • Development and validation of a UPLC-PDA method for quantifying ceftazidime in dried blood spots.: This paper outlines a validated ultra-performance liquid chromatography photodiode array (UPLC-PDA) method for the quantification of ceftazidime, demonstrating its application and accuracy in analyzing dried blood samples (Lv et al., 2024).

  • A facile fabric phase sorptive extraction method for monitoring chloramphenicol residues in milk samples.: Describes a new method using fabric phase sorptive extraction for the efficient monitoring of chloramphenicol in milk, highlighting its simplicity and effectiveness (Ben Ayed et al., 2024).

  • Study of sample preparation influence on bacterial lipids profile in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.: This research investigates how different sample preparation methods affect the lipid profiles of bacteria analyzed by MALDI-TOF MS, providing insights into optimizing protocols for better accuracy (Arendowski et al., 2024).

  • Simple and robust LC-MS/MS method for quantification of colistin methanesulfonate and colistin in human plasma for therapeutic drug monitoring.: This article details a robust and straightforward liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous determination of colistin methanesulfonate and colistin in human plasma, useful in clinical settings (Kim et al., 2023).

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Preparation Note

Product filtered through a 0.2 μm filter

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

保管分類

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - (Acetonitrile)

flash_point_c

2 °C - (Acetonitrile)


試験成績書(COA)

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以前この製品を購入いただいたことがある場合

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資料

Learn the tips and tricks of selecting and preparing a suitable mobile phase buffer for your HPLC separations and method developments for samples that contain ionizable compounds.

Determination of plasma protein binding using a SupelTM C18 pin device based BioSPME method for efficient sample preparation, along with a comparison to the equilibrium dialysis method.

Learn about Supel™ BioSPME C18 high-throughput devices to determine plasma protein binding and decrease the sample preparation time to less than an hour.

The application note describes a comparative analysis of plasma protein binding results for free/bound drugs using two different sample extraction steps, with and without agitation.

グローバルトレードアイテム番号

カタログ番号GTIN
1.59014.250004054839190674
1.59014.400004054839190698

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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