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Merck

178479

Anti-Apolipoprotein E Goat pAb

liquid, Calbiochem®

別名:

Anti-ApoE antibody

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この商品について

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
Citations:
22

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製品名

Anti-Apolipoprotein E Goat pAb, liquid, Calbiochem®

biological source

goat

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human, rat, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(ELISA (1:8000)
Immunoprecipitation
Free Floating Sections )

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Application

ELISA (1:8000)

Immunoprecipitation (see comments)

Free Floating Sections (see application references)

Disclaimer

Toxicity: Standard Handling (A)

General description

Anti-Apolipoprotein E, goat polyclonal, recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins. It is validated for ELISA, immunoprecipitation, and free-floating sections.
Goat polyclonal antibody supplied as serum that has been defibrinated, delipidized and dialyzed against a Tris-HCl buffer. Recognizes the apolipoprotein E protein.
Recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins.
  • Antibody Target Gene Symbol: APOE
  • Target Synonym: AD2, AI255918, APOE2, APOE4, APOEA, APOLIPOPROTEIN E, LDLCQ5, LPG, MGC1571
  • Entrez Gene Name: apolipoprotein E
  • Hu Entrez ID: 348 (Related Antibodies: NE1004)
  • Mu Entrez ID: 11816
  • Rat Entrez ID: 25728

    • Immunogen

    Human
    purified recombinant human apolipoprotein E

    Other Notes

    Monospecific as determined by immunoelectrophoresis (IEP) against twice concentrated pooled human serum. This antibody has also been reported to work with immunoprecipitation. Variables associated with assay conditions will dictate the proper working dilution.

    Packaging

    Please refer to vial label for lot-specific concentration.

    Physical form

    In 500 mM NaCl, 50 mM Tris-HCl, pH 7.5.

    Preparation Note

    Following initial thaw, aliquot and freeze (-20°C).

    Legal Information

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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    保管分類

    10 - Combustible liquids

    wgk

    WGK 1

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    適用法令

    試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

    178479-UL: + 178479-5ML: + 178479-500UL: + 178479-0ML:

    jan

    試験成績書（COA）

    製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

    以前この製品を購入いただいたことがある場合

    文書ライブラリで、最近購入した製品の文書を検索できます。

    文書ライブラリにアクセスする

    Emilie L Castranio et al.
    Neurobiology of disease, 105, 1-14 (2017-05-16)
    Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer's disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset
    Suzanne E Wahrle et al.
    The Journal of biological chemistry, 279(39), 40987-40993 (2004-07-23)
    ABCA1 is an ATP-binding cassette protein that transports cellular cholesterol and phospholipids onto high density lipoproteins (HDL) in plasma. Lack of ABCA1 in humans and mice causes abnormal lipidation and increased catabolism of HDL, resulting in very low plasma apoA-I
    Michael Landowski et al.
    Proceedings of the National Academy of Sciences of the United States of America, 116(9), 3703-3711 (2019-02-28)
    One of the strongest susceptibility genes for age-related macular degeneration (AMD) is complement factor H (CFH); however, its impact on AMD pathobiology remains unresolved. Here, the effect of the principal AMD-risk-associated CFH variant (Y402H) on the development and progression of
    Ema Ozaki et al.
    Experimental eye research, 217, 108953-108953 (2022-01-30)
    As the resident immune cells in the retina, microglia play important homeostatic roles in retinal immune regulation and neuroprotection. However, chronic microglia activation is a common hallmark of many degenerative retinal diseases. The semi-synthetic tetracycline antibiotic, minocycline, appears to inhibit
    Shan-May Yong et al.
    Scientific reports, 4, 6580-6580 (2014-10-11)
    The effect of ApoE on NMDAR-dependent ERK/CREB signaling is isoform-dependent, and ApoE4 accelerates memory decline in ageing. However, this isoform-dependent function on neuronal signaling during ageing is unclear. In this study, we have examined NMDAR-associated ERK/CREB signal transduction in young
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    グローバルトレードアイテム番号

    カタログ番号GTIN
    178479-500ULCN04055977205183

    ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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