251600
Daidzein
Inactive analog of Genistein.
別名:
Daidzein, 4ʹ,7-Dihydroxyisoflavone, Casein Kinase II Inhibitor X
製品名
Daidzein, Inactive analog of Genistein.
SMILES string
O1c2c(ccc(c2)O)C(=O)C(=C1)c3ccc(cc3)O
InChI
1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI key
ZQSIJRDFPHDXIC-UHFFFAOYSA-N
description
Merck USA index - 14, 2801
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white to off-white
solubility
DMSO: 200 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Cell permeable: no
Primary Target
MiaPaC-2, PANC-1
MiaPaC-2, PANC-1
Product does not compete with ATP.
Reversible: no
Target IC50: 45 µM, 75 µM for inhibiting the growth of MiaPaC-2 and PANC-1 cells, respectively
Disclaimer
Toxicity: Irritant (B)
General description
Inactive analog of Genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss/3T3 cells by inhibiting casein kinase II activity. Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively).
Inactive analog of genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. Inhibits epidermal growth factor (EGF) receptor autophosphorylation (IC50 >300 µM). Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively).
Other Notes
Guo, J-M., et al. 2004. World J. Gastroenterol.10, 860.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol.7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem.262, 5592.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol.7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem.262, 5592.
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C) under an inert gas. DMSO stock solutions are stable for up to 2 months at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 251600-25MGCN | 04055977198539 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）