371725
GPR43 Agonist
>98% (HPLC), solid
別名:
GPR43 (FFA2) Agonist, (S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide
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この商品について
実験式（ヒル表記法）:
C21H21ClN2OS
CAS番号:
分子量:
384.92
MDL number:
UNSPSC Code:
51111800
NACRES:
NA.77
製品名
GPR43 (FFA2) Agonist, The GPR43 (FFA2) Agonist controls the biological activity of GPR43. This small molecule/inhibitor is primarily used for Biochemicals applications.
assay
>98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 50 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
Disclaimer
Toxicity: Standard Handling (A)
General description
A phenylacetamide compound that acts as an allosteric agonist of FFA2 (GPR43), demonstrating a left-shifted acetate dose response (IC50 = 0.7 µM) and 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays.
Other Notes
Wang, Y., et al. 2009. Bioorg. Med. Chem. Lett.20, 493.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
José Luís Fachi et al.
The Journal of experimental medicine, 217(3) (2019-12-27)
Antibiotic-induced dysbiosis is a key predisposing factor for Clostridium difficile infections (CDIs), which cause intestinal disease ranging from mild diarrhea to pseudomembranous colitis. Here, we examined the impact of a microbiota-derived metabolite, short-chain fatty acid acetate, on an acute mouse
Yongguo Li et al.
Cell reports, 29(12), 4099-4113 (2019-12-19)
Recruitment of brite/beige cells, known as browning of white adipose tissue (WAT), is an efficient way to turn an energy-storing organ into an energy-dissipating one and may therefore be of therapeutic value in combating obesity. However, a comprehensive understanding of
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 371725-10MGCN | 04055977213270 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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