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Merck

535140

Protease Inhibitor Cocktail III

Animal-Free, liquid, for the inhibition of aspartic, cysteine, serine proteases and aminopeptidases

別名:

Animal free Protease inhibitor

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この商品について

UNSPSC Code:
12352200
NACRES:
NA.54
Form:
liquid
Solubility:
water: soluble
Storage temp.:
−20°C
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製品名

Protease Inhibitor Cocktail Set III, Animal-Free, Protease Inhibitor Cocktail Set III, Animal-Free, is a cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine & serine proteases & aminopeptidases.

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

solubility

water: soluble

shipped in

wet ice

storage temp.

−20°C

Biochem/physiol Actions

Cell permeable: no
Primary Target
Aspartic, cysteine, and serine proteases as well as aminopeptidases
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Irritant (B)

General description

A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases. This cocktail is recommended for use with mammalian cell and tissue extracts. Each vial contains 100 mM AEBSF, HCl (Cat. No. 101500), 80 µM Aprotinin (Cat. No. 616371), 5 mM Bestatin (Cat. No. 200484), 1.5 mM E-64 (Cat. No. 324890), 2 mM Leupeptin Hemisulfate (Cat. No. 108975) and 1 mM Pepstatin A (Cat. No. 516482). Available as 1 ml vial or a set of 5 x 1 ml.

Physical form

In 1 ml DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

保管分類

10 - Combustible liquids

flash_point_f

188.6 °F

flash_point_c

87 °C


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

535140-1SET: + 535140-1SML: + 535140-1ML:

jan


試験成績書(COA)

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文書ライブラリにアクセスする

Kimberly D Herman et al.
Frontiers in immunology, 13, 956991-956991 (2022-08-16)
Dysregulated neutrophilic inflammation can be highly destructive in chronic inflammatory diseases due to prolonged neutrophil lifespan and continual release of histotoxic mediators in inflamed tissues. Therapeutic induction of neutrophil apoptosis, an immunologically silent form of cell death, may be beneficial
Changhwan Yeo et al.
International journal of molecular sciences, 23(8) (2022-04-24)
Osteoarthritis (OA) causes persistent pain, joint dysfunction, and physical disability. It is the most prevalent type of degenerative arthritis, affecting millions of people worldwide. OA is currently treated with a focus on pain relief, inflammation control, and artificial joint surgery.
Jessica A O Zimmerman et al.
RSC medicinal chemistry, 12(2), 203-212 (2021-05-29)
Glucocorticoids (GCs) are widely used, potent anti-inflammatory and chemotherapeutic drugs. They work by binding to the glucocorticoid receptor (GR), a ligand-activated transcription factor, inducing translocation to the nucleus and regulation of genes that influence a variety of cellular activities. Despite
Danielle T Phillippi et al.
Particle and fibre toxicology, 19(1), 10-10 (2022-02-10)
The gut microbiota plays a vital role in host homeostasis and is associated with inflammation and cardiovascular disease (CVD) risk. Exposure to particulate matter (PM) is a known mediator of inflammation and CVD and is reported to promote dysbiosis and
David M Box et al.
Children (Basel, Switzerland), 9(3) (2022-03-26)
In utero inflammation is associated with bronchopulmonary dysplasia (BPD) in preterm infants. We hypothesized that maternal tobacco exposure (TE) might induce placental neutrophil infiltration, increasing the risk for BPD. We compared the composite outcome of BPD and death in a

グローバルトレードアイテム番号

カタログ番号GTIN
535140-1MLCN04055977076141
535140-1SETCN07790788051235

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