539131
Protease Inhibitor Cocktail I
lyophilized, for the inhibition of aspartic, cysteine, serine, metalloproteases and aminopeptidases
別名:
Protease Inhibitor Mix, Protease inhibitor
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この商品について
UNSPSC Code:
12352200
NACRES:
NA.28
Form:
lyophilized
Solubility:
water: soluble
Storage temp.:
−20°C
製品名
Protease Inhibitor Cocktail Set I, A cocktail of five protease inhibitors that will inhibit a broad range of proteases and esterases. Supplied with a data sheet.
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
solubility
water: soluble
shipped in
wet ice
storage temp.
−20°C
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General description
Protease Inhibitor Cocktail Set I A is specially formulated containing five protease inhibitors that will inhibit a broad range of proteases and esterases.
Application
Protease Inhibitor Cocktail Set I – Calbiochem has been used in lysis buffer to lyse cells and perform western blotting.
Protease Inhibitor Cocktail Set I have been used as a supplement in:
- cold radioimmunoprecipitation assay (RIPA) buffer to prepare cell lysates for western blotting
- RIPA lysis buffer to extract total protein from rat liver tissues and AML12 cells
- sucrose solution to homogenize mice cortices for myelin isolation
Biochem/physiol Actions
Inhibits a broad range of proteases and esterases.
Protease inhibitor cocktails and specific protease inhibitors are essential tools utilized by scientists in various proteomic studies. These studies encompass protein expression, characterization, biomarker discovery, mapping post-translational modifications, protein expression profiling, and quantitative protein measurement. The application of a protease inhibitor cocktail or protease inhibitors guarantees the preservation of protein integrity, facilitating downstream analysis and characterization.
Features and Benefits
- Protease Inhibitor Cocktails offer protection of target protein against degradation in crude extracts
- Ready for reconstitution
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Reconstitute each vial with 1 ml dH2O to yield a 100X stock solution.
Other Notes
The presence of EDTA may interfere with the purification of His•Tag fusion proteins if a cell extract is applied directly to IMAC resins.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Eye Dam. 1 - Skin Corr. 1A - STOT RE 2 Inhalation
target_organs
Respiratory Tract
保管分類
8B - Non-combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Class I Designated Chemical Substances
prtr
Substances Subject to be Indicated Names
ishl_indicated
Substances Subject to be Notified Names
ishl_notified
US1539131-10VL: + 539131-1VL: + 539131-100UL: + 539131-10VL:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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Journal of Alzheimer's disease : JAD, 80(2), 813-829 (2021-02-14)
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Molecules (Basel, Switzerland), 25(11) (2020-06-14)
There are still controversies regarding the correlation between the beneficial effects for health and the administration of isolated compounds or crude extracts in therapeutic applications. Campomanesia xanthocarpa, found in the Brazilian Cerrado, demonstrated beneficial effects in metabolic disorders associated with
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Frontiers in oncology, 9, 1446-1446 (2020-01-11)
Aerobic glycolysis is the main pathway for energy metabolism in cancer cells. It provides energy and biosynthetic substances for tumor progression and metastasis by increasing lactate production. Lactate dehydrogenase A (LDHA) promotes glycolysis process by catalyzing the conversion of pyruvate
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Cellular and molecular gastroenterology and hepatology, 12(1), 81-98 (2021-01-27)
Fulminant hepatitis (FH) is a clinical syndrome characterized by sudden and severe liver dysfunction. Dot1L, a histone methyltransferase, is implicated in various physiologic and pathologic processes, including transcription regulation and leukemia. However, the role of Dot1L in regulating inflammatory responses
関連コンテンツ
An Introduction to Inhibitors and Their Biological Applications
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 539131-10VLCN | 07790788051273 |
| 539131-1VLCN | 04055977195378 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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