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Merck

AB15452

Anti-MAP2 Antibody

CHEMICON®, chicken polyclonal

別名:

Microtubule associated protein 2

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この商品について

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
mouse
Application:
ICC, IHC
Citations:
13
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製品名

Anti-MAP2 Antibody, Chemicon®, from chicken

biological source

chicken

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Map2(17756)

Immunogen

Synthetic peptides corresponding to different regions of the human/mouse MAP2 protein.

Application

Anti-MAP2 Antibody detects level of MAP2 & has been published & validated for use in IC, IH.
Immunohistochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed tissue.

Immunocytochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism

Biochem/physiol Actions

MAP2 [Microtubule associated protein 2]
Other species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.

Physical form

Affinity purified chicken immunoglobulin. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
ImmunoAffinity Purified

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

保管分類

12 - Non Combustible Liquids


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

AB15452:

jan



試験成績書(COA)

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以前この製品を購入いただいたことがある場合

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Yun Yang et al.
Nature communications, 13(1), 159-159 (2022-01-12)
Abnormalities in brain glucose metabolism and accumulation of abnormal protein deposits called plaques and tangles are neuropathological hallmarks of Alzheimer's disease (AD), but their relationship to disease pathogenesis and to each other remains unclear. Here we show that succinylation, a
Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity.
Kapfhamer D, Berger KH, Hopf FW, Seif T, Kharazia V, Bonci A, Heberlein U
The Journal of Neuroscience null
Maria Vedunova et al.
Frontiers in cellular neuroscience, 7, 149-149 (2013-09-26)
The extracellular matrix (ECM) plays an important role in use-dependent synaptic plasticity. Hyaluronic acid (HA) is the backbone of the neural ECM, which has been shown to modulate α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate (AMPA) receptor mobility, paired-pulse depression, L-type voltage-dependent Ca(2+) channel (L-VDCC) activity



グローバルトレードアイテム番号

カタログ番号GTIN
AB1545204053252405099