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Merck

HFIB1-100K

MILLIPLEX® Human Fibrosis 3-Plex Panel 1

Configurable Human Fibrosis 3-Plex Panel

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この商品について

NACRES:
NA.47
UNSPSC Code:
12161503
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species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 95-96%, standard curve range: 10-40,000 pg/mL
(for COMP), standard curve range: 2-10,000 pg/mL
(for IL-18BPa), standard curve range: 6-25,000 pg/mL
(for Uteroglobin), inter-assay cv: <20%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

input

cell culture supernatant
serum

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Fibrosis is a pathological wound healing response that is common to many chronic diseases and injuries. The abnormal wound healing response of fibrosis involves the excessive accumulation of the extracellular matrix components responsible for the formation of scar tissue. Progressive tissue scarring causes alterations to normal organ structure leading to dysfunction and failure. Fibrosis and related diseases are responsible for an increasing burden of morbidity and mortality worldwide. This panel of fibrosis-related biomarkers enables researchers to advance understanding of the complex processes associated with fibrotic diseases, including but not limited to idiopathic pulmonary fibrosis, liver fibrosis, and lung fibrosis.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 3 analytes in human serum, plasma, and tissue culture supernatants.

Analytes included: IL-18 Binding Protein A (IL-18BPa), Cartilage Oligomeric Matrix Protein (COMP), and Uteroglobin

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Targeted 3-plex Fibrosis Biomarker Panel: Simultaneously quantify three critical fibrosis-related proteins (IL-18BPa, COMP, and Uteroglobin) in a single assay, providing comprehensive insights into fibrotic disease progression and therapeutic response monitoring.
  • Configurable Panel: Design your personalized multiplex kit by selecting specific analytes most relevant to your fibrosis research objectives, optimizing cost-effectiveness while maintaining superior assay performance and reducing unnecessary measurements.
  • Comprehensive Fibrosis Pathway Analysis: Investigate complex mechanisms underlying idiopathic pulmonary fibrosis, liver fibrosis, cardiac fibrosis, and other fibrotic conditions by simultaneously monitoring key regulatory proteins involved in extracellular matrix remodeling and tissue scarring processes.
  • Drug Development and Biomarker Discovery: Accelerate anti-fibrotic therapeutic development by identifying novel biomarker signatures and validating potential drug targets across multiple fibrotic disease models and patient populations.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

保管分類

10 - Combustible liquids

wgk

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Please refer to KIT Component information

pdsc

Please refer to KIT Component information

prtr

Please refer to KIT Component information

fsl

Please refer to KIT Component information

ishl_indicated

Please refer to KIT Component information

ishl_notified

Please refer to KIT Component information

cart

キットコンポーネントの情報を参照してください

jan


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

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グローバルトレードアイテム番号

カタログ番号GTIN
HFIB1-100K-0104065265449694
HFIB1-100K-0204065265449700
HFIB1-100K-0304065265449717

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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