製品名
Bovine Serum Albumin Fraction V, heat shock, fatty acid free, from bovine serum
biological source
bovine
assay
≥98%
form
lyophilized
packaging
pkg of 100 g
manufacturer/tradename
Roche
pH
~7.0
shipped in
wet ice
storage temp.
2-8°C
Quality Level
Analysis Note
Purity: ≥98% albumin (electrophoresis), ≥98% protein
Contaminants: ≤1.2mg total fatty acids/g dry powder, ≤30ppm heavy metals, immunoglobulins are not detectable (by Ouchterlony)
Contaminants: ≤1.2mg total fatty acids/g dry powder, ≤30ppm heavy metals, immunoglobulins are not detectable (by Ouchterlony)
Application
- Pharmacological assays; ion-binding, transport, or immunological studies
- Fatty acid and lipid research
- Stabilization of proteins and enzymes against proteolysis and denaturation
Biochem/physiol Actions
The fatty acids that are insoluble in circulating plasma are transported primarily by serum. The human serum albumin and bovine serum albumin share 76% sequence homology. Being the most abundant protein in the circulatory system, it participates in the maintenance of blood pH and carries several endogenous and exogenous compounds, including fatty acids, metal, amino acids, steroids and drugs.
Features and Benefits
Moisture: ≤5%
General description
BSA is a single polypeptide chain consisting of about 583 amino acid residues and no carbohydrates. At pH 5-7, it contains 17 intra-chain disulfide bridges and one sulfhydryl group.
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Prakrith Vijey et al.
Platelets, 29(6), 583-588 (2018-07-27)
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Putnam F, et al.
The Plasma Proteins: Structure, Function, and Genetic Control, 5 (2012)
Emilio P Mottillo et al.
Methods in enzymology, 538, 263-278 (2014-02-18)
Intracellular lipolysis is an important cellular process in key metabolic tissues, and while much is known about the enzymatic basis of lipolysis, our understanding of how these processes are organized and regulated within cells is incomplete. Lipolysis takes place on
Rachel D Penrod et al.
Journal of neuroscience methods, 200(1), 1-13 (2011-06-16)
Dendritic spines of striatal Medium Spiny Neurons (MSNs) receive converging dopaminergic and glutamatergic inputs. These spines undergo experience-dependent structural plasticity following repeated drug administration and during disease states like Huntington's and Parkinson's. Thus, understanding the molecular mechanisms leading to structural
Bill X Huang et al.
Journal of the American Society for Mass Spectrometry, 15(8), 1237-1247 (2004-07-28)
Serum albumin is the principal transporter of fatty acids that are otherwise insoluble in circulating plasma. While the crystal structure of human serum albumin (HSA) as well as its binding with fatty acids has been characterized, the three dimensional structure
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