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この商品について
実験式(ヒル表記法):
C12H17ClN4OS · HCl
CAS番号:
分子量:
337.27
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
34058006
UNSPSC Code:
12352209
EC Number:
200-641-8
MDL number:
Beilstein/REAXYS Number:
3851771
biological source
synthetic
Quality Level
agency
tested according to Ph. Eur.
assay
98.5-101.0% anhydrous basis
form
solid
mp
250 °C (dec.) (lit.)
solubility
alcohol: soluble 1 gm in 100 ml (95%), alcohol: soluble 1 gm in 315 ml (Absolute), glycerol: soluble 1 gm in 18 ml, water: soluble 1 g/mL, benzene: insoluble, chloroform: insoluble, diethyl ether: insoluble, hexane: insoluble, methanol: very soluble, propylene glycol: soluble
storage temp.
2-8°C
SMILES string
CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
InChI
1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
InChI key
DPJRMOMPQZCRJU-UHFFFAOYSA-M
Application
Thiamine hydrochloride has been used as a keratin salts medium supplement for culturing log-phase fungus. It has also been used as a supplement of VB medium the minimal medium of Vogel and Bonner.
Biochem/physiol Actions
Thiamine hydrochloride is a hydrochloride salt form of thiamine (Vitamin B1). It is crucial for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis.
Thiamine hydrochloride is a cheap, non-toxic and efficient catalyst for the synthesis of amidoalkyl naphthols. It inhibits the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. Additionally, thiamine hydrochloride addition to apple juice concentrates reduces its patulin content.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
保管分類
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
G Apodaca et al.
Infection and immunity, 57(10), 3081-3090 (1989-10-01)
Trichophyton rubrum is the most common dermatophyte of humans and normally colonizes the superficial layers of the epidermis (stratum corneum). Several proteinases with a possible role in the metabolism of host proteins have been purified from this fungus. The regulation
Serafettin Yazici et al.
Die Nahrung, 46(4), 256-257 (2002-09-13)
Thiamine hydrochloride, pyridoxine hydrochloride and calcium-d-pantothenate were applied apple juice concentrates (AJC) at various doses in order to reduce the patulin content. AJC samples containing high levels of patulin were stored at 22 +/- 2 degrees C and 4 degrees
Thermodynamics of (solute+ solute) and (solute+ solvent) interactions of homologous series of amino acids with thiamine hydrochloride in aqueous medium at T=(305.15, 310.15, 315.15) K: A volumetric and acoustic approach
Kumar H and Behal I
The Journal of Chemical Thermodynamics, 102, 48-62 (2016)
