06206
オクタノイル-L-カルニチン
analytical standard
別名:
(2R)-3-カルボキシ-N,N,N-トリメチル-2-[(1-オキソオクチル)オキシ]-1-プロパンアミニウム 分子内塩, L-カルニチンオクタノイルエステル, C8-カルニチン
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この商品について
実験式（ヒル表記法）:
C15H29NO4
CAS番号:
分子量:
287.40
UNSPSC Code:
41116107
NACRES:
NB.21
Beilstein/REAXYS Number:
5955761
InChI
1S/C15H29NO4/c1-5-6-7-8-9-10-15(19)20-13(11-14(17)18)12-16(2,3)4/h13H,5-12H2,1-4H3/t13-/m1/s1
SMILES string
C[N+](C)(C)C[C@H](OC(CCCCCCC)=O)CC([O-])=O
InChI key
CXTATJFJDMJMIY-CYBMUJFWSA-N
grade
analytical standard
assay
≥97.0% (HPLC)
optical activity
[α]/D -17±2°, c = 0.1 in H2O
shelf life
limited shelf life, expiry date on the label
impurities
≤10% water
application(s)
clinical testing
format
neat
storage temp.
2-8°C
Quality Level
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関連するカテゴリー
General description
Octanoyl-L-carnitine is a medium-chain endogenous ester of L-carnitine, obtained via acylcarnitine family transferase.
Application
Octanoyl-L-carnitine may be used as an analytical standard in the following:
It may be used as a test material for investigating its rate of oxidation by mitochondria, isolated from the livers of fed, starved and glucagon treated virgin and lactating rats.
- Separation and identification of underivatized octanoyl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).
- Quantification of the analyte in biological samples of patients treated with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS). The feasibility of adding L-carnitine to the peritoneal dialysis (PD) solution in APD-treated end-stage renal disease patients is investigated.
It may be used as a test material for investigating its rate of oxidation by mitochondria, isolated from the livers of fed, starved and glucagon treated virgin and lactating rats.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
06206-BULK: + 06206-10MG: + 06206-VAR: + 06206-50MG:
jan
The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria
Zammit AV
The Biochemical Journal, 190(2), 293-300 (1980)
L-Carnitine moiety assay: an up-to-date reappraisal covering the commonest methods for various applications
Marzo A and Curti S
Journal of Chromatography. B, Biomedical Sciences and Applications, 702(1-2), 1-20 (1997)
L-Carnitine status in end-stage renal disease patients on automated peritoneal dialysis
Liberato DL , et al.
Journal of Nephrology, 27(6), 699-706 (2014)
Minzhi Peng et al.
Journal of chromatography. A, 1319, 97-106 (2013-10-31)
A simple HPLC-MS/MS method has been established to separate and identify underivatized acylcarnitine isomers. Human plasma samples were deproteinized and concentrated. Acylcarnitines were separated on a reverse phase column and detected with triple quadrupole linear ion trap mass spectrometry. Deuterium-labeled
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