11569
3,4-ジヒドロキシフェニル酢酸
analytical standard
別名:
DOPAC, ホモプロトカテキン酸
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この商品について
化学式:
(HO)2C6H3CH2CO2H
CAS番号:
分子量:
168.15
UNSPSC Code:
77101502
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-024-1
Beilstein/REAXYS Number:
2211017
MDL number:
InChI
1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChI key
CFFZDZCDUFSOFZ-UHFFFAOYSA-N
SMILES string
OC(=O)Cc1ccc(O)c(O)c1
grade
analytical standard
assay
≥97.0% (HPLC), 97.0-103.0% (T)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
127-130 °C (lit.)
application(s)
pharmaceutical
format
neat
Quality Level
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Application
3,4-Dihydroxyphenylacetic acid may be used as a reference standard for the determination of 3,4-dihydroxyphenylacetic acid in rat samples by high-performance liquid chromatography with electrochemical detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
11569-BULK: + 11569-25MG: + 11569-VAR:
jan
Simultaneous determination of 3, 4?dihydroxyphenylalanine, 5?hydroxytryptophan, dopamine, 4?hydroxy?3?methoxyphenylalanine, norepinephrine, 3, 4?dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5?hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high?performance liquid chromatography with electrochemical detection.
Wagner J, et al.
Journal of Neurochemistry, 38(5), 1241-1254 (1982)
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Biomolecules & therapeutics, 28(3), 282-291 (2020-04-28)
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Neuroinflammation is one of the driving forces of progressive neurodegeneration in Parkinson's disease (PD). The metabolomics approach has been proved highly useful in identifying potential therapeutic targets. Here, to identify inflammation-relevant treatment targets for PD, mass spectrometry-based untargeted metabolomics was
Sandy Stayte et al.
PloS one, 10(4), e0124325-e0124325 (2015-04-23)
Parkinson's disease (PD) is a chronic neurodegenerative disease characterized by a significant loss of dopaminergic neurons within the substantia nigra pars compacta (SNpc) and a subsequent loss of dopamine (DA) within the striatum. Despite advances in the development of pharmacological
Bing Han et al.
Parkinsonism & related disorders, 20(11), 1191-1195 (2014-09-16)
Parkinson's disease (PD) is a progressive neurodegenerative movement disorder that is caused predominantly by the degeneration of the nigrostriatal dopaminergic pathway. Lateral habenula (LHb) has efferent projections that terminate in the substantia nigra pars compacta (SNpc) and electrical stimulation of
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