15604
尿素
puriss., meets analytical specification of Ph. Eur., BP, USP, 99.0-100.5%, 99.0-101.0% (calc. on dry substance)
別名:
カルバミド, カルボニルジアミド
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この商品について
化学式:
NH2CONH2
CAS番号:
分子量:
60.06
UNSPSC Code:
12352100
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-315-5
Beilstein/REAXYS Number:
635724
MDL number:
Assay:
99.0-100.5%, 99.0-101.0% (calc. on dry substance)
Form:
solid
grade
puriss.
Quality Level
assay
99.0-100.5%, 99.0-101.0% (calc. on dry substance)
form
solid
quality
meets analytical specification of Ph. Eur., BP, USP
impurities
alkalic reac. substances, complies, ≤0.001% heavy metals (as Pb), ≤0.04% insoluble in ethanol, ≤0.05% ammonium (NH4), ≤0.1% biuret(carbamylurea)
ign. residue
≤0.1% (as SO4)
loss
≤1.0% loss on drying, 105 °C, 1 h
mp
132-135 °C
solubility
H2O: soluble 480 g/L at 20 °C
density
1.335 g/mL at 25 °C (lit.)
anion traces
chloride (Cl-): ≤10 mg/kg, sulfate (SO42-): ≤50 mg/kg
cation traces
Fe: ≤0.5 mg/kg
suitability
in accordance for appearance of solution, in accordance for identity
functional group
amine
SMILES string
NC(N)=O
InChI
1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChI key
XSQUKJJJFZCRTK-UHFFFAOYSA-N
General description
Urea is a colorless, odorless solid. It has prism-like crystals. It forms insoluble nitrate salts with nitric acid and oxalate salts with oxalic acid. On reaction with alkanes or substituted alkanes, it affords crystal-lattice inclusion compounds.
Urea can be prepared from ammonia and carbon-dioxide, via Haber-Bosch process. It can also be used to prepare urea-formaldehyde resins, via condensation reaction.
Urea can be prepared from ammonia and carbon-dioxide, via Haber-Bosch process. It can also be used to prepare urea-formaldehyde resins, via condensation reaction.
Application
タンパク質の変性剤として、また不溶性タンパク質や変性タンパク質に対する穏やかな可溶化剤として用いられています。6 M塩酸グアニジンですでに変性された封入体などのサンプルからタンパク質を復元する用途に適しています。変性タンパク質を天然型または活性型にリフォールディングさせる際に、塩酸グアニジンやジチオスレイトール(DTT)とともに使用することができます。
Urea has been used in the following studies:
- Synthesis of SnO2 nanoparticles.
- Synthesis of urethanes, ureides and semicarbazides.
- Denaturation of protein isolated from Saccharomyces cerevisiae Y15696 strain
- Protein electrophoretic studies.
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保管分類
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Braun D, et al. et al.
Polymer Synthesis: Theory and Practice: Fundamentals, Methods, Experiments ; with 31 Tables (2001)
Nova I and Tronconi E et al.
Urea-SCR Technology for deNOx after treatment of Diesel Exhausts (2014)
Genna L Andrews et al.
Analytical chemistry, 83(13), 5442-5446 (2011-05-31)
The TripleTOF 5600 System, a hybrid quadrupole time-of-flight mass spectrometer, was evaluated to explore the key figures of merit in generating peptide and protein identifications that included spectral acquisition rates, data quality, proteome coverage, and biological depth. Employing a Saccharomyces