16587
ダイゼイン
analytical standard
別名:
4′,7-ジヒドロキシイソフラボン, 7-ヒドロキシ-3-(4-ヒドロキシフェニル)-4H-1-ベンゾピラン-4-オン, 7-ヒドロキシ-3-(4-ヒドロキシフェニル)クロモン, イソアウロスタチン
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この商品について
実験式（ヒル表記法）:
C15H10O4
CAS番号:
分子量:
254.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-635-4
Beilstein/REAXYS Number:
231523
MDL number:
製品名
ダイゼイン, analytical standard
InChI
1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI key
ZQSIJRDFPHDXIC-UHFFFAOYSA-N
SMILES string
Oc1ccc(cc1)C2=COc3cc(O)ccc3C2=O
grade
analytical standard
assay
≥97.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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関連するカテゴリー
Biochem/physiol Actions
ダイズイソフラボンダイゼインは、7,12-ジメチルベンズ[a]アントラセン (DMBA)が引き起こす酸化損傷から肝細胞を保護します。DMBAによって下方制御されたカタラーゼおよびスーパーオキシドジスムターゼ活性がダイゼインによって回復しました。
Packaging
底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。
Application
Daidzein was used as standard in determination of daidzein and genistein, in soybean food using in-tube solid-phase microextraction coupled to high-performance liquid chromatography (in-tube SPME–HPLC). It was also used as reference standard in determination of isoflavones in red clover using high-performance liquid chromatography–UV–electrospray ionization-mass spectrometric detector (HPLC–UV–ESI-MSD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Daidzein is an endocrine-active estrogenic isoflavone. This phytoestrogen is capable to bind to estrogen to exert estrogenic effects in vivo. It can naturally be found in soybean seed and flour.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro.
Casanova, Mercedes, et al.
Toxicological Sciences, 51.2, 236-244 (1999)
Determination of isoflavones in red clover and related species by high-performance liquid chromatography combined with ultraviolet and mass spectrometric detection.
Wu Q, Wang M, Simon JE.
Journal of Chromatography A, 1016(2), 195-209 (2003)
Determination of daidzein and genistein in soybean foods by automated on-line in-tube solid-phase microextraction coupled to high-performance liquid chromatography.
Mitani K, Narimatsu S, Kataoka H.
Journal of Chromatography A, 986(2), 169-177 (2003)
Katherine A Jackman et al.
Current medicinal chemistry, 14(26), 2824-2830 (2007-11-30)
Isoflavones are an important class of phytoestrogens that are found at extrememly high levels in soy. Up until recently, daidzein and genistein were considered to be the most important and hence most studied isoflavones, however more recently attention has shifted
Ivonne M C M Rietjens et al.
Molecular nutrition & food research, 57(1), 100-113 (2012-11-24)
Isoflavones are phytoestrogens that have been linked to both beneficial as well as adverse effects in relation to cell proliferation and cancer risks. The present article presents an overview of these seemingly contradicting health effects and of mechanisms that could
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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