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Merck

34092

レスベラトロール

analytical standard

別名:

3,4′,5-トリヒドロキシ-trans-スチルベン, 5-[(1E)-2-(4-ヒドロキシフェニル)エテニル]-1,3-ベンゼンジオール

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この商品について

実験式(ヒル表記法):
C14H12O3
CAS番号:
分子量:
228.24
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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製品名

レスベラトロール, analytical standard

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

SMILES string

Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2

InChI key

LUKBXSAWLPMMSZ-OWOJBTEDSA-N

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

Quality Level

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Application

COX-1の選択的阻害剤です。
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Resveratrol has been used as a phenolic analytical standard to determine its content in oat flour tarhana and different varieties of chicory using high-performance liquid chromatography with diode array detection (HPLC-DAD). It has also been used as an analytical standard to investigate its effectiveness in modulating several signaling pathways that are involved in carcinogenesis, via determining its anti-tumor potential in colorectal cancer as a proapoptotic agent in colorectal cancer cell lines, including HCT116, CO115 and SW48.

General description

Resveratrol, a non-flavonoid polyphenolic compound, is widely found in the skin of red grapes, nuts, berries, Polygonum cuspidatum root, etc. It is reportedly known to exhibit pharmacological properties including anti-cancer, anti-inflammatory, antioxidant, neuroprotectant, anti-atherogenic property and reduces the synthesis of pro-atherosclerotic substances.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

保管分類

10 - Combustible liquids

wgk

WGK 3

flash_point_f

>392.0 °F - closed cup - (External MSDS)

flash_point_c

> 200.0 °C - closed cup - (External MSDS)

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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文書ライブラリにアクセスする

Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
Lu R and Serrero G
Journal of Cellular Physiology, 179, 297-304 (1999)
The impact of drying techniques on phenolic compound, total phenolic content and antioxidant capacity of oat flour tarhana
Degirmencioglu N, et al.
Food Chemistry, 194, 587-594 (2016)
Biological effects of resveratrol
Fremont L
Life Sciences, 66, 663-673 (2000)
Philippe de Medina et al.
Journal of medicinal chemistry, 48(1), 287-291 (2005-01-07)
We developed new stilbene derivatives of resveratrol (E)-1-(4'-hydroxyphenyl)-2-(3,5-dihydroxyphenyl)ethene) selective for AhR and devoid of affinity for ER. Among the 24 stilbenes synthesized, all display a higher affinity than resveratrol for AhR. (E)-1-(4'-Trifluoromethylphenyl)-2-(3,5-ditrifluoromethylphenyl)ethene (4e), (E)-1-(4'-methoxyphenyl)-2-(3,5-dichlorophenyl)ethene (4j), and (E)-1-(4'-chlorophenyl)-2-(3,5-dichlorophenyl)ethene (4b) are selective
W Zhang et al.
European journal of medicinal chemistry, 42(6), 841-850 (2007-02-24)
Agents that induce the activity of phase II enzymes play an important role in intervening with the carcinogenic process at the initiation stage. Resveratrol is well known for its chemopreventive activity against major stages of carcinogenesis. In this study, several

資料

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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