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Merck

37921

4-Epianhydrotetracycline hydrochloride

VETRANAL®, analytical standard

別名:

(4R,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride

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この商品について

実験式（ヒル表記法）:
C22H22N2O7 · HCl
CAS番号:
4465-65-0
分子量:
462.88
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329755729
MDL number:
MFCD00151455
Beilstein/REAXYS Number:
3840711

主要文書

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製品名

4-Epianhydrotetracycline hydrochloride, VETRANAL®, analytical standard

InChI

1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28;/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30);1H/t11-,16+,22-;/m0./s1

SMILES string

Cl[H].[H][C@@]12Cc3c(C)c4cccc(O)c4c(O)c3C(=O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H]2N(C)C

InChI key

XBSQEFHDCDFNJU-MOMXNFOMSA-N

grade

analytical standard

agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

100

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関連するカテゴリー

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Chemical structure: tetracycline

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
BCCG1172
BCCD0402
BCBW8576
BCBS4721V
BCBS4721

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Ute Seidel et al.
The journal of physical chemistry. B, 111(21), 6006-6014 (2007-05-08)
Molecular-dynamics simulations have been used to investigate the mechanism of induction of a mutant (revTetR) of the tetracycline repressor protein (TetR) that shows the reverse phenotype (i.e., it is induced in the absence of tetracyclines and not in their presence).
G B Zavilgelsky et al.
Biochemistry. Biokhimiia, 73(8), 906-911 (2008-09-09)
Anti-restriction proteins ArdA and Ocr are specific inhibitors of type I restriction-modification enzymes. The IncI1 transmissible plasmid ColIb-P9 ardA and bacteriophage T7 0.3(ocr) genes were cloned in pUC18 vector. Both ArdA (ColIb-P9) and Ocr (T7) proteins inhibit both restriction and
Marcus Resch et al.
Nucleic acids research, 36(13), 4390-4401 (2008-07-01)
Today's proteome is the result of innumerous gene duplication, mutagenesis, drift and selection processes. Whereas random mutagenesis introduces predominantly only gradual changes in protein function, a case can be made that an abrupt switch in function caused by single amino
Martha Ines Burgos et al.
Biological & pharmaceutical bulletin, 34(8), 1301-1306 (2011-08-02)
Tetracycline (TC) derivatives are extensively used as antibiotics in human and animal medicine and, very recently, they have been screened as anti-amyloidogenic drugs. Anhydrotetracycline (AHTC) is one of the major degradation products of TC that has been linked to several
Markus W Obrist et al.
Plasmid, 68(1), 33-42 (2012-03-27)
In Yersinia, the most commonly used expression vectors for genetic studies such as gene complementation do not effectively allow for both induction and repression of gene expression. Additionally, there is no expression system available that can be induced in bacteria
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