プロゲステロン

Name: プロゲステロン
Brand: SIAL

VETRANAL^®, analytical standard

別名:

4-プレグネン-3,20-ジオン

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この商品について

実験式（ヒル表記法）:

C₂₁H₃₀O₂

CAS番号:

57-83-0

分子量:

314.46

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329756616

EC Number:

200-350-6

Beilstein/REAXYS Number:

1915950

MDL number:

MFCD00003658

主要文書

すべての文書を表示

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製品名

プロゲステロン, VETRANAL^®, analytical standard

Quality Level

100

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

SMILES string

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

grade

analytical standard

product line

VETRANAL^®

assay

99.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

128-132 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... ESR1(2099), PGR(5241)

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Biochem/physiol Actions

子宮内膜の成熟と分泌活性を誘導し、排卵を抑制します。

子宮内膜の成熟と分泌活性を誘導し、排卵を抑制します。プロゲステロンは乳がんの原因にかかわっています。

Other Notes

黄体で産生されるステロイドホルモンです。

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS08

signalword

Danger

hcodes

H351,H360FD,H362

pcodes

P202 - P260 - P263 - P264 - P280 - P308 + P313

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number

BCCK4203

BCBZ9566

適切なバージョンが見つかりませんか。

特定のバージョンが必要な場合は、ロット番号またはバッチ番号で特定の証明書を検索できます。

COAを検索

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Complex biological pattern of fertility hormones in children and adolescents: a study of healthy children from the CALIPER cohort and establishment of pediatric reference intervals.

Danijela Konforte et al.

Clinical chemistry, 59(8), 1215-1227 (2013-05-03)

Pediatric endocrinopathies are commonly diagnosed and monitored by measuring hormones of the hypothalamic-pituitary-gonadal axis. Because growth and development can markedly influence normal circulating concentrations of fertility hormones, accurate reference intervals established on the basis of a healthy, nonhospitalized pediatric population

Premenopausal serum sex hormone levels in relation to breast cancer risk, overall and by hormone receptor status - results from the EPIC cohort.

Rudolf Kaaks et al.

International journal of cancer, 134(8), 1947-1957 (2013-10-25)

Results from prospective studies on premenopausal serum hormone levels in relation to breast cancer risk have been inconclusive, especially with regard to tumor subtypes. Using a case-control study nested within the prospective European Prospective Investigation into Cancer and Nutrition (EPIC)

Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC).

Rudolf Kaaks et al.

Journal of the National Cancer Institute, 97(10), 755-765 (2005-05-19)

Contrasting etiologic hypotheses about the role of endogenous sex steroids in breast cancer development among premenopausal women implicate ovarian androgen excess and progesterone deficiency, estrogen excess, estrogen and progesterone excess, and both an excess or lack of adrenal androgens (dehydroepiandrosterone

Probiotic Lactobacillus rhamnosus GR-1 supernatant prevents lipopolysaccharide-induced preterm birth and reduces inflammation in pregnant CD-1 mice.

Siwen Yang et al.

American journal of obstetrics and gynecology, 211(1), 44-44 (2014-02-04)

The objective of this study was to determine the effect of probiotic Lactobacillus rhamnosus GR-1 supernatant (GR-1 SN) on lipopolysaccharide-induced preterm birth (PTB) and outputs of cytokines, chemokines, and progesterone in pregnant CD-1 mice. We compared PTB rates after intrauterine

Progesterone signalling in breast cancer: a neglected hormone coming into the limelight.

Cathrin Brisken

Nature reviews. Cancer, 13(6), 385-396 (2013-05-25)

Understanding the biology of the breast and how ovarian hormones impinge on it is key to rational new approaches in breast cancer prevention and therapy. Because of the success of selective oestrogen receptor modulators (SERMs), such as tamoxifen, and aromatase

プロゲステロン

VETRANAL®, analytical standard

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この商品について

主要文書

特性

製品名

Quality Level

InChI key

InChI

SMILES string

grade

product line

assay

shelf life

technique(s)

mp

application(s)

format

Gene Information

関連するカテゴリー

詳細

Biochem/physiol Actions

Other Notes

Application

Legal Information

安全性情報

pictograms

signalword

hcodes

pcodes

Hazard Classifications

保管分類

wgk

flash_point_f

flash_point_c

ppe

資料

試験成績書（COA）

以前この製品を購入いただいたことがある場合

参考文献

テクニカルサービス

VETRANAL^®, analytical standard