49761
スペルミジン
analytical standard
別名:
1,8-ジアミノ-4-アザオクタン, N-(3-アミノプロピル)-1,4-ジアミノブタン
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この商品について
化学式:
NH2(CH2)3NH(CH2)4NH2
CAS番号:
分子量:
145.25
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
204-689-0
Beilstein/REAXYS Number:
1698591
MDL number:
製品名
スペルミジン, analytical standard
InChI
1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
InChI key
ATHGHQPFGPMSJY-UHFFFAOYSA-N
SMILES string
NCCCCNCCCN
grade
analytical standard
assay
≥97.5% (NT)
≥99.0% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.479 (lit.)
density
0.925 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
storage temp.
2-8°C
Quality Level
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関連するカテゴリー
Biochem/physiol Actions
神経型一酸化窒素合成酵素（nNOS）を阻害します。DNAに結合し沈殿させ、DNA結合タンパク質の精製に使用できます。T4ポリヌクレオチドキナーゼ活性を刺激します。
神経型一酸化窒素合成酵素（nNOS）を阻害します。DNAに結合し沈殿させます。T4ポリヌクレオチドキナーゼ活性を刺激します。
Disclaimer
滅菌が必要な場合は、オ-トクレ-ブではなく、濾過滅菌を行ってください。スペルミジンは経時的に脱アミノ化するので、溶液は凍結保存してください。溶液は用時調製してください。
Packaging
底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Spermidine may be used as one of the reference standard for the determination of spermidine in biological samples by high performance liquid chromatography-electrospray ionization–ion trap tandem mass spectrometry (HPLC–ESI–ITMS/MS).
General description
Spermidine is a naturally occurring polyamine compound commonly found in food. It is essential for cell growth and survival.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
保管分類
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
233.6 °F - closed cup
flash_point_c
112 °C - closed cup
Determination of putrescine, cadaverine, spermidine and spermine in different chemical matrices by high performance liquid chromatography?electrospray ionization?ion trap tandem mass spectrometry (HPLC?ESI?ITMS/MS).
Ibarra A A G, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1002, 176-184 (2015)
Micro-scale strategy to detect spermine and spermidine by MALDI?TOF MS in foods and identification of apoptosis-related proteins by nano-flow UPLC?MS/MS after treatment with spermine and spermidine
Su H H, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 978, 131-137 (2015)
Varun K Gupta et al.
Nature neuroscience, 16(10), 1453-1460 (2013-09-03)
Age-dependent memory impairment is known to occur in several organisms, including Drosophila, mouse and human. However, the fundamental cellular mechanisms that underlie these impairments are still poorly understood, effectively hampering the development of pharmacological strategies to treat the condition. Polyamines
Eugenia Morselli et al.
Aging, 1(12), 961-970 (2010-02-17)
Although autophagy has widely been conceived as a self-destructive mechanism that causes cell death, accumulating evidence suggests that autophagy usually mediates cytoprotection, thereby avoiding the apoptotic or necrotic demise of stressed cells. Recent evidence produced by our groups demonstrates that
Andrew Breakspear et al.
The Plant cell, 26(12), 4680-4701 (2014-12-21)
Nitrogen-fixing rhizobia colonize legume roots via plant-made intracellular infection threads. Genetics has identified some genes involved but has not provided sufficient detail to understand requirements for infection thread development. Therefore, we transcriptionally profiled Medicago truncatula root hairs prior to and
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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