92136
ゲニステイン
analytical standard
別名:
4′,5,7-トリヒドロキシイソフラボン, 5,7-ジヒドロキシ-3-(4-ヒドロキシフェニル)-4H-1-ベンゾピラン-4-オン
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この商品について
実験式（ヒル表記法）:
C15H10O5
CAS番号:
分子量:
270.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-174-9
Beilstein/REAXYS Number:
263823
MDL number:
製品名
ゲニステイン, analytical standard
format
neat
InChI
1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
SMILES string
Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O
InChI key
TZBJGXHYKVUXJN-UHFFFAOYSA-N
grade
analytical standard
assay
≥97% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
storage temp.
2-8°C
Quality Level
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関連するカテゴリー
Biochem/physiol Actions
チロシンタンパク質キナ-ゼの阻害剤です。他のタンパク質キナ-ゼの反応においては、ATPの競合的阻害剤として作用します。抗血管新生剤であり、血管新生の調節に関与する遺伝子の転写をダウンレギュレ-トします。
Packaging
底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Genistein, a naturally occurring soy isoflavone, is a dietary protein tyrosine kinase (PTK) inhibitor. It is found to possess anticarcinogenic properties.
Other Notes
This compound is commonly found in plants of the genus: glycyrrhiza
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Genistein inhibits renal cancer progression through long non-coding RNA HOTAIR suppression
Imai-Sumida M, et al.
Clinical Cancer Research, 3449-3449 (2017)
Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells
GP and SB
Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research, 7, 1345-1351 (1996)
Alexandra Mamagkaki et al.
PloS one, 16(4), e0250599-e0250599 (2021-04-28)
The objective of this study is to improve and optimize the formulation of Genistein in capsules in order to result in a better pharmacokinetic profile comparing to existing commercial products. In order to do this, five different formulations of Genistein
Sonia de Pascual-Teresa et al.
The Journal of nutritional biochemistry, 17(4), 257-264 (2005-08-20)
If soy isoflavones are to be effective in preventing or treating a range of diseases, they must be bioavailable, and thus understanding factors which may alter their bioavailability needs to be elucidated. However, to date there is little information on
M Uehara et al.
The Journal of steroid biochemistry and molecular biology, 72(5), 273-282 (2000-05-24)
A time-resolved fluoroimmunoassay (TR-FIA), with europium labeled phytoestrogens as tracers, was developed for the quantitative determination of enterolactone, genistein and daidzein in human urine. The aim was to create a method for the screening of large populations in order to
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