Hoveyda-Grubbs Catalyst^® M720 ChemBeads

We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Greener Chemistry. ChemBeads are advanced solid-coated beads for high-throughput experimentation in various chemical applications. They enable precise dispensing of solid reagents, allowing researchers to conduct reactions with minimal material use, thus supporting waste prevention and catalysis principles while ensuring accuracy and reproducibility. This technology enhances efficiency and streamlines experimental processes in chemistry. Click here for more information.

The ChemBeads product of second generation, phosphine-free Hoveyda-Grubbs Catalyst^® M720. The catalyst has comparable reactivity to the first generation, but initiates more readily at lower temperatures. Efficient for metathesis of electron-deficient substrates including fluorinated olefins. Demonstrated in multiple large-scale pharmaceutical applications. Loaded on glass beads for use in high-throughput expermentation (HTE).

Hoveyda-Grubbs Catalyst^® M720 has be used as:
A catalyst for olefin cross-metathesis with fluorinated olefins (CM).
A catalyst for ring-closing metathesis (RCM).
A catalyst for ring-opening metathesis (ROM).
A catalyst for a sequence of a metathesis reaction and subsequent dihydroxylation of the newly formed double bond.
A ROM catalyst in mechanochemical polymer synthesis.
A catalyst in the total synthesis of the Diterpenes (+)-Randainin D and (+)-Barekoxide.
ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

For general uses, product is also available in powdered form (569755)

Grubbs Catalyst is a registered trademark of Umicore AG & Co. KG