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この商品について
実験式(ヒル表記法):
C9H13N3O5
CAS番号:
分子量:
243.22
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
89175
製品名
シトシンβ-D-アラビノフラノシド, European Pharmacopoeia (EP) Reference Standard
InChI key
UHDGCWIWMRVCDJ-CCXZUQQUSA-N
SMILES string
NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O
InChI
1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
grade
pharmaceutical primary standard
API family
cytarabine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Gene Information
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関連するカテゴリー
Biochem/physiol Actions
Ara-CはDNAに取り込まれてI型トポイソメラ-ゼとの間に切断複合体を形成することでDNAを断片化し、DNAの複製を阻害します。RNA合成には影響を及ぼしません。抗白血病薬。
General description
この製品は薬局方標準品です。発行元の薬局方により製造・供給されています。MSDSを含む製品情報などの詳しい情報は、発行元の薬局方のウェブサイトよりご確認ください。
Application
Cytarabine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - Skin Sens. 1
保管分類
11 - Combustible Solids
wgk
WGK 3
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Although induction chemotherapy comprising high-dose cytarabine (HiDAC) in combination with idarubicin and etoposide or 'ICE' for adult acute myeloid leukaemia (AML) produces a complete remission rate of nearly 80%, gastrointestinal toxicity is significant. Omission of etoposide may produce similar clinical
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MiR34A, B and C have been implicated in lymphomagenesis, but information on their role in normal CD19+ B-cells (PBL-B) and de novo diffuse large B-cell lymphoma (DLBCL) is limited. We show that in normal and activated B-cells miR34A-5p plays a
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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