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この商品について
実験式（ヒル表記法）:
C22H29FO5
CAS番号:
分子量:
392.46
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-003-9
Beilstein/REAXYS Number:
2066651
MDL number:
biological source
synthetic
grade
pharmaceutical primary standard
agency
EP
API family
dexamethasone
packaging
pkg of 50 mg
manufacturer/tradename
EDQM
storage condition
protect from light
mp
262-264 °C (lit.)
solubility
water: <0.1 g/L
application(s)
pharmaceutical (small molecule)
format
neat
shipped in
ambient
SMILES string
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InChI
1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key
UREBDLICKHMUKA-CXSFZGCWSA-N
Gene Information
human ... NR3C1(2908)
General description
この製品は薬局方標準品です。発行元の薬局方により製造・供給されています。MSDSを含む製品情報などの詳しい情報は、発行元の薬局方のウェブサイトよりご確認ください。
Application
Dexamethasone EP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques.
Biochem/physiol Actions
グルココルチコイド・抗炎症剤。T細胞の生存、成長、分化を調節します。一酸化窒素合成酵素の誘導を阻害します。
グルココルチコイド抗炎症薬です。
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Dexamethasone
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 4961-4963 (2021)
Spectrophotometric resolution of ternary mixtures of Dexamethasone, Polymyxin B and Trimethoprim in synthetic and pharmaceutical formulations
Gallego JML and Arroyo JP
Analytica Chimica Acta, 437(2), 247-257 (2001)
Determination of prednisolone, dexamethasone and hydrocortisone in pharmaceutical formulations and biological fluid samples by voltammetric techniques using b-cyclodextrin modified carbon paste electrode
Balaji K, et al.
African Journal of Pharmacy and Pharmacology, 2(8), 157-166 (2008)