ログインで組織・契約価格をご覧ください。
サイズを選択してください
この商品について
実験式(ヒル表記法):
C23H31NO2 · HCl
CAS番号:
分子量:
389.96
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
製品名
プロアジフェン 塩酸塩, analytical standard, ≥95%
InChI
1S/C23H31NO2.ClH/c1-4-17-23(20-13-9-7-10-14-20,21-15-11-8-12-16-21)22(25)26-19-18-24(5-2)6-3;/h7-16H,4-6,17-19H2,1-3H3;1H
SMILES string
Cl.CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2
InChI key
FHIKZROVIDCMJA-UHFFFAOYSA-N
grade
analytical standard
assay
≥95%
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
122-123 °C
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
Quality Level
Gene Information
human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
類似した製品をお探しですか? 訪問 製品比較ガイド
Application
プロアジフェン塩酸塩は、ガスクロマトグラフィ質量分析法(GC-MS)を用いるヒト尿サンプル中のO-デスメチルトラマドール、トラマドールおよびN-デスメチルトラマドールのような鎮痛薬の定量の内部標準として使用することができます。
適切な装置技術に関するさらなる情報については製品の分析試験証明書をご参照ください。さらなるサポートについてはTechnical Service(技術サービス)までお問い合わせください。
Biochem/physiol Actions
グリベンクラミド感受性K+チャンネルを遮断します。神経性一酸化窒素シンタ-ゼおよびチトクロ-ムP450を阻害します。
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Simultaneous determination of tramadol, O-desmethyltramadol and N-desmethyltramadol in human urine by gas chromatography?mass spectrometry
El-Sayed Y A-A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 926, 9-15 (2013)
Michael R Franklin et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(12), 2539-2546 (2008-09-19)
When incubated with human liver microsomes, 2-diethylaminoethyl-2,2-diphenylvalerate-HCl (SKF525A) undergoes cytochrome P450 (P450)-dependent oxidative N-deethylation to the secondary amine metabolite 2-ethylaminoethyl-2,2-diphenylvalerate (SKF8742). P450-selective inhibitors indicated CYP3As catalyzed this reaction, and the deethylation rate correlated best with the CYP3A activity across a
Xian Wu et al.
Toxicological sciences : an official journal of the Society of Toxicology, 157(2), 410-420 (2017-04-04)
Human neural progenitor cells are capable of independent, directed differentiation into astrocytes, oligodendrocytes and neurons and thus offer a potential cell source for developmental neurotoxicity (DNT) systems. Human neural progenitor-derived astrocyte-neuron cocultured at defined ratios mimic cellular heterogeneity and interaction
David Fuchs et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(4), 158611-158611 (2020-01-10)
Trihydroxyoctadecenoic acids (TriHOMEs) are linoleic acid-derived lipid mediators reported to be dysregulated in obstructive lung disease. In contrast to many other oxylipins, TriHOME biosynthesis in humans is still poorly understood. The association of TriHOMEs with inflammation prompted the current investigation
María Eugenia Letelier et al.
Toxicology in vitro : an international journal published in association with BIBRA, 25(7), 1310-1313 (2011-05-17)
Adverse reactions of acetaminophen have been associated to oxidative stress, which may be elicited by reactive oxygen species (ROS) and/or production of the metabolite NAPQI. Both phenomena would arise through the activity of liver cytochrome P450 (CYP450) system, but their
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら(テクニカルサービス)