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この商品について
実験式（ヒル表記法）:
C13H19NO4S
CAS番号:
分子量:
285.36
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
製品名
プロベネシド, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
SMILES string
CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
InChI key
DBABZHXKTCFAPX-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
probenecid
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... SLC22A11(55867), SLC22A6(9356), SLC22A8(9376)
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関連するカテゴリー
General description
この製品は薬局方標準品です。発行元の薬局方により製造・供給されています。MSDSを含む製品情報などの詳しい情報は、発行元の薬局方のウェブサイトよりご確認ください。
Packaging
この製品は発行元の薬局方による供給としてお届けします。現在の単位量については、EDQM reference substance catalogueをご覧ください。
Application
Probenecid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Beth Soletsky et al.
Hypertension (Dallas, Tex. : 1979), 60(5), 1148-1156 (2012-09-26)
Epidemiologic studies, animal models, and preliminary clinical trials in children implicate uric acid in the development of essential hypertension. Controversy remains as to whether the observations indicate a general mechanism or a surrogate phenomenon. We sought to determine whether uric
Hiroshi Watanabe et al.
Kidney international, 83(4), 582-592 (2013-01-18)
The accumulation of p-cresyl sulfate (PCS), a uremic toxin, is associated with the mortality rate of chronic kidney disease patients; however, the biological functions and the mechanism of its action remain largely unknown. Here we determine whether PCS enhances the
Olivia Perwitasari et al.
Antimicrobial agents and chemotherapy, 57(1), 475-483 (2012-11-07)
Influenza A virus infection is a major global health concern causing significant mortality, morbidity, and economic loss. Antiviral chemotherapeutics that target influenza A virus are available; however, rapid emergence of drug-resistant strains has been reported. Consequently, there is a burgeoning
Gerhard Dahl et al.
Brain research, 1487, 150-159 (2012-07-10)
Pannexin1 (Panx1) originally was discovered as a gap junction related protein. However, rather than forming the cell-to-cell channels of gap junctions, Panx1 forms a mechanosensitive and highly ATP permeable channel in the cell membrane allowing the exchange of molecules between
Nathan Robbins et al.
Cardiovascular toxicology, 12(1), 1-9 (2011-09-23)
Probenecid was initially developed with the goal of reducing the renal excretion of antibiotics, specifically penicillin. It is still used for its uricosuric properties in the treatment in gout, but its clinical relevance has sharply fallen and is rarely used
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