P4722
ピリドキシン 塩酸塩
meets USP testing specifications
別名:
PN HCl, アデルミン 塩酸塩, ビタミンB6 塩酸塩, ピリドキソール 塩酸塩
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この商品について
実験式（ヒル表記法）:
C8H11NO3 · HCl
CAS番号:
分子量:
205.64
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
34058008
UNSPSC Code:
12352205
EC Number:
200-386-2
MDL number:
Beilstein/REAXYS Number:
3632435
製品名
ピリドキシン 塩酸塩, meets USP testing specifications
InChI key
ZUFQODAHGAHPFQ-UHFFFAOYSA-N
InChI
1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
SMILES string
Cl[H].Cc1ncc(CO)c(CO)c1O
biological source
synthetic (organic)
agency
USP/NF
meets USP testing specifications
assay
98.0-102.0% dry basis
form
powder
color
white
mp
214-215 °C (lit.)
application(s)
pharmaceutical (small molecule)
Quality Level
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Application
Pyridoxine hydrochloride has been used to test its neuroprotective functionality in traumatic brain injury (TBI) rats. It has also been used as a reference standard to quantify vitamin B6 in feed and digesta samples using high-performance liquid chromatography(HPLC).
Biochem/physiol Actions
Pyridoxine plays a key role in metabolism both carbohydrates and amino acids. It supports brain development and its deficiency levels may lead to depletion of γ-aminobutyric acid (GABA) levels. Pyridoxine catalyzes the neurotransmitter biosynthesis like dopamine and serotonin. Pyridoxine in excess or deficient may lead to neuropathy.
General description
Vitamin B group is water-soluble and exists in six forms namely the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. The food sources of vitamin B6 include grains, nuts, fruits, vegetables and meat.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Nutritional neuropathies
Hammond N, et al.
Neurologic Clinics, 31(2), 477-477 (2013)
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin
Calderon-Ospina CA, et al.
CNS Neuroscience & Therapeutics (2019)
Pyridoxine administration improves behavioral and anatomical outcome after unilateral contusion injury in the rat
Kuypers NJ and Hoane MR
Journal of Neurotrauma, 27(7), 1275-1282 (2010)
Effects of forage family on apparent ruminal synthesis of B vitamins in lactating dairy cows
Castagnino DS, et al.
Journal of Dairy Science, 99(3), 1884-1894 (2016)
Determination of vitamin B6 (pyridoxine) in pharmaceutical preparations by cyclic voltammetry at a copper (II) hexacyanoferrate (III) modified carbon paste electrode
Teixeira MFS, et al.
Journal of the Brazilian Chemical Society, 14(2), 316-321 (2003)
資料
Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.
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