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PHR1004

イブプロフェン

Name: イブプロフェン
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

α-メチル-4-(イソブチル)フェニル酢酸, (±)-2-(4-イソブチルフェニル)プロパン酸

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この商品について

実験式（ヒル表記法）:

C₁₃H₁₈O₂

CAS番号:

15687-27-1

分子量:

206.28

NACRES:

NA.24

PubChem Substance ID:

329823035

UNSPSC Code:

41116107

EC Number:

239-784-6

MDL number:

MFCD00010393

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特性

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. I0020000, traceable to USP 1335508

API family

ibuprofen

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CC(C)Cc1ccc(cc1)C(C)C(O)=O

InChI

1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

InChI key

HEFNNWSXXWATRW-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742), PTGS2(5743)

詳細

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Ibuprofen is a substituted arylpropionic acid, used as a non-steroidal anti-inflammatory drug (NSAID).

Application

Ibuprofen may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry and chromatography techniques.

Ibuprofen may be used as a standard in the quantitative determination of ibuprofen in samples of human plasma using high performance liquid chromatography (HPLC). It may also be used as a reference standard in the determination of ibuprofen in dog plasma using liquid chromatography (LC).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

シクロオキシゲナーゼ (COX) のインヒビターであり、COX-2よりもCOX-1に対して強く作用します。

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Analysis Note

このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC0253 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

GHS07

signalword

Warning

hcodes

H302,H319,H335

pcodes

P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

保管分類

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c