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Merck

PHR1093

スルファニルアミド

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

p-アミノベンゼンスルホンアミド

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この商品について

化学式:
H2NC6H4SO2NH2
CAS番号:
分子量:
172.20
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
39093202
UNSPSC Code:
41116107
EC Number:
200-563-4
MDL number:
Beilstein/REAXYS Number:
511852
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InChI key

FDDDEECHVMSUSB-UHFFFAOYSA-N

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

SMILES string

Nc1ccc(cc1)S(N)(=O)=O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1633007

API family

sulfanilamide

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

~Approximately 166 °C, 164-166 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Application

It was used in a study to demonstrate photodecomposition in aqueous solution of cutaneous photosensitizing agents with the help of spin traps 5, 5-dimethyl-1-pyrroline-1-oxide.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfanilamide Melting Point Standard, also called Sulfanilamide, is an antibacterial drug. It blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Sulfanilamide Melting Point Standard also called Sulfanilamide is an antibacterial drug.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB1410 in the slot below. This is an example certificate only and may not be the lot that you receive.

保管分類

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

PHR1093-1G-PW: + PHR1093-1G-BULK: + PHR1093-1G: + 02344-1G-BULK: + 02344-1G:

jan


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS?II. SPIN TRAPPING OF PHOTOLYSIS PRODUCTS FROM SULFANILAMIDE AND 4-AMINOBENZOIC ACID USING 5, 5-DIMETHYL-1-PYRROLINE-1-OXIDE.
Chignell, Colin F., et al.
Photochemistry and Photobiology, 34.2 , 147-156 (1981)
Xian-Long Wang et al.
European journal of medicinal chemistry, 45(10), 4631-4639 (2010-08-17)
A series of novel sulfanilamide-derived 1,2,3-triazole compounds were synthesized in excellent yields via 1,3-dipolar cycloaddition and confirmed by MS, IR and NMR spectra as well as elemental analyses. All the compounds were screened in vitro for their antibacterial and antifungal
Fei Liu et al.
Organic letters, 12(4), 868-871 (2010-01-19)
The synthesis of benzofused sultams and/or fluorinated sulfonamides, starting from N-allylic sulfonamides, was performed in superacid HF/SbF(5), through superelectrophilic activation. A dramatic effect of superacid composition on the selectivity of the reaction was shown and applied to the synthesis of
Ramazan Demirdağ et al.
Bioorganic & medicinal chemistry, 21(6), 1522-1525 (2012-09-15)
Carbonic anhydrase (CA, EC: 4.2.1.1) was purified from sheep kidney by affinity chromatography on a Sepharose 4B-tyrosine-sulfanilamide column. By means of two consecutive procedures, the enzyme (sCA) was purified 227.61-fold with a yield of 60.75%, and a specific activity of
Sevgi Kolayli et al.
Journal of enzyme inhibition and medicinal chemistry, 26(6), 895-900 (2011-03-09)
An α-carbonic anhydrase (CA, EC 4.2.1.1) was purified and characterized kinetically from erythrocytes of the sturgeon Acipenser gueldenstaedti, an endangered species. The sturgeon enzyme (AgCA) showed kinetic parameters for the CO(2) hydration reaction comparable with those of the human erythrocytes

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