PHR1123

ミリスチン酸イソプロピル

Name: ミリスチン酸イソプロピル
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

イソプロピルテトラデカノアート, ミリスチン酸イソプロピルエステル

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この商品について

化学式:

CH₃(CH₂)₁₂COOCH(CH₃)₂

CAS番号:

110-27-0

分子量:

270.45

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823144

EC Number:

203-751-4

Beilstein/REAXYS Number:

1781127

MDL number:

MFCD00008982

主要文書

すべての文書を表示

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InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. I0750000, traceable to USP 1350400

API family

isopropyl myristate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

300

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

Isopropyl myristate is an ester of isopropyl alcohol myristic acid. It is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It also finds applications as a flavoring agent in the food industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA7001 in the slot below. This is an example certificate only and may not be the lot that you receive.

保管分類

10 - Combustible liquids

wgk

awg

flash_point_f

>302.0 °F

flash_point_c

> 150 °C

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

第4類:引火性液体 + 第三石油類 + 危険等級III + 非水溶性液体

fsl

PHR1123-1G: + PHR1123-1G-PW:

jan

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA）を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

CRC Handbook of Food, Drug, and Cosmetic Excipients (1992)

Investigation of microemulsion microstructures and their relationship to transdermal permeation of model drugs: ketoprofen, lidocaine, and caffeine.

Ji Zhang et al.

International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)

In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant

Preparation of high solubilizable microemulsion of naproxen and its solubilization mechanism.

Qingping Tian et al.

International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)

To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and

Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling.

T N Engelbrecht et al.

Skin pharmacology and physiology, 25(4), 200-207 (2012-05-23)

In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol, palmitic acid and cholesterol sulfate

Effect of vehicles on the maximum transepidermal flux of similar size phenolic compounds.

Qian Zhang et al.

Pharmaceutical research, 30(1), 32-40 (2012-08-28)

In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized

ミリスチン酸イソプロピル

Pharmaceutical Secondary Standard; Certified Reference Material

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この商品について

主要文書

特性

InChI key

InChI

SMILES string

grade

agency

API family

CofA

technique(s)

Quality Level

bp

mp

density

application(s)

format

storage temp.

関連するカテゴリー

詳細

General description

Application

Analysis Note

Other Notes

安全性情報

保管分類

wgk

flash_point_f

flash_point_c

適用法令

第4類:引火性液体 + 第三石油類 + 危険等級III + 非水溶性液体

PHR1123-1G: + PHR1123-1G-PW:

資料

試験成績書（COA）

以前この製品を購入いただいたことがある場合

参考文献

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