PHR1153
クエン酸トリエチル
Pharmaceutical Secondary Standard; Certified Reference Material
別名:
クエン酸エチル
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この商品について
化学式:
HOC(COOC2H5)(CH2COOC2H5)2
CAS番号:
分子量:
276.28
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-070-7
Beilstein/REAXYS Number:
1801199
MDL number:
製品名
クエン酸トリエチル, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
DOOTYTYQINUNNV-UHFFFAOYSA-N
InChI
1S/C12H20O7/c1-4-17-9(13)7-12(16,11(15)19-6-3)8-10(14)18-5-2/h16H,4-8H2,1-3H3
SMILES string
CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1683606
vapor density
9.7 (vs air)
vapor pressure
1 mmHg ( 107 °C)
API family
triethyl citrate
CofA
current certificate can be downloaded
Quality Level
greener alternative product characteristics
Less Hazardous Chemical Syntheses
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.442 (lit.)
bp
235 °C/150 mmHg (lit.)
density
1.14 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
greener alternative category
storage temp.
2-30°C
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Triethyl citrate can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
General description
Triethyl citrate is an ester of citric acid and is commonly used as a plasticizer in pharmaceutical coatings including tablets, capsules, beads and granules for masking taste. It is also used as a flavoring agent in food.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product can replace highly toxic diluents in membrane preparation and thus aligns with "Less Hazardous Chemical Syntheses". Click here for more information.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8988 in the slot below. This is an example certificate only and may not be the lot that you receive.
Values of analytes vary lot to lot.
保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_f
311.0 °F - closed cup
flash_point_c
155 °C - closed cup
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Oral Strip Technology: A review
Jaiswal, Hema
Indian Journal of Pharmaceutical and Biological Research, 2(2), 130-130 (2014)
Ethylcellulose--A Pharmaceutical Excipient with Multidirectional Application in Drug Dosage Forms Development
Wasilewska K and Winnicka K
Materials, 12(20), 3386-3386 (2019)
Detection and quantification of low-molecular-weight aldehydes in pharmaceutical excipients by headspace gas chromatography
Li Z, et al.
Journal of Chromatography A, 1104(1-2), 1-10 (2006)
Development and validation of a gradient HPLC method for the determination of clindamycin and related compounds in a novel tablet formulation.
Platzer DJ, White BA.
Journal of Pharmaceutical and Biomedical Analysis, 41(1), 84-88 (2006)
M R Abbaspour et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 68(3), 747-759 (2007-11-06)
One challenge in tableting of sustained-release multiparticulates is maintaining the desired drug release after compaction. The aim of this study was to design sustained-release ibuprofen tablets which upon oral ingestion rapidly disintegrate into sustained-release pellets in which the integrity of
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