PHR1216
セバシン酸ジブチル
Pharmaceutical Secondary Standard; Certified Reference Material
別名:
セバシン酸ジブチルエステル
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この商品について
化学式:
[-(CH2)4CO2(CH2)3CH3]2
CAS番号:
分子量:
314.46
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-672-5
Beilstein/REAXYS Number:
1798308
MDL number:
製品名
セバシン酸ジブチル, Pharmaceutical Secondary Standard; Certified Reference Material
InChI
1S/C18H34O4/c1-3-5-15-21-17(19)13-11-9-7-8-10-12-14-18(20)22-16-6-4-2/h3-16H2,1-2H3
InChI key
PYGXAGIECVVIOZ-UHFFFAOYSA-N
SMILES string
CCCCOC(=O)CCCCCCCCC(=O)OCCCC
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1187091
API family
dibutyl sebacate
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.441 (lit.)
bp
178-179 °C/3 mmHg (lit.)
density
0.936 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dibutyl sebacate is a commonly used plasticizer, which can be synthesized by the reaction of butyl alcohol and sebacyl chloride or by the distillation of sebacic acid with butyl alcohol in the presence of concentrated hydrochloric acid in benzene solution.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9029 in the slot below. This is an example certificate only and may not be the lot that you receive.
保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_f
366.8 °F - open cup
flash_point_c
186 °C - open cup
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Burdock AG et al.
Encyclopedia of Food & Color Additives, 1 (1997)
E Oh et al.
International journal of pharmaceutics, 188(2), 203-219 (1999-10-16)
The surface free energy parameters of ethylcellulose (EC) films were determined using the Lifshitz-van der Waals/acid-base approach and the influence of plasticizers on their surface energetics was assessed. Films were prepared by dip-coating glass slides in organic solvents containing EC
A Wyss et al.
Biotechnology and bioengineering, 91(2), 227-236 (2005-05-26)
The activity of penicillin acylase has been studied in aqueous and organic solvents, as free enzyme as well as immobilized within the membrane of liquid-core capsules. The activity of the enzyme is inhibited by the accumulation of the products of
Sapna N Makhija et al.
Journal of controlled release : official journal of the Controlled Release Society, 89(1), 5-18 (2003-04-16)
A controlled porosity osmotic pump-based drug delivery system has been described in this study. Unlike the elementary osmotic pump (EOP) which consists of an osmotic core with the drug surrounded by a semipermeable membrane drilled with a delivery orifice, controlled
D Serp et al.
Biotechnology and bioengineering, 82(1), 103-110 (2003-02-06)
The bioconversion of L-phenylalanine to 2-phenylethanol by Saccharomyces cerevisiae in fed-batch experiments has shown that concentrations of 2-phenylethanol of >2.9 g/L have a negative impact on the oxidative capacity of the yeast. Without tight control on ethanol production, and hence
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