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Merck

PHR1241

L-メチオニン

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

(S)-2-アミノ-4-(メチルメルカプト)酪酸, L-2-アミノ-4-(メチルチオ)酪酸

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この商品について

化学式:
CH3SCH2CH2CH(NH2)CO2H
CAS番号:
63-68-3
分子量:
149.21
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823245
EC Number:
200-562-9
Beilstein/REAXYS Number:
1722294
MDL number:
MFCD00063097

主要文書

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InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

SMILES string

CSCC[C@H](N)C(O)=O

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. M0960000, traceable to USP 1411504

API family

methionine & derivatives

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

284 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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関連するカテゴリー

General description

品質管理の認定を受けた製品番号医薬品の2次標準は、薬局方の1次標準に対する便利で対費用効果の高い代替品を医薬品研究室と製薬企業に提供します。

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

L-Methionine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by ion chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9045 in the slot below. This is an example certificate only and may not be the lot that you receive.

保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

PHR1241-1G: + PHR1241-1G-PW:

jan

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Ion-chromatographic determination of carbocisteine in pharmaceuticals based on non-suppressed conductimetric detection
Megoulas NC and Koupparis MA
Journal of Chromatography A, 1026(1-2), 167-174 (2004)
B Almé et al.
Journal of lipid research, 18(3), 339-362 (1977-05-01)
A method is described for quantitative analysis of bile acids in urine. Urine is acidified and bile acids are extracted on an Amberlite XAD-2 column. Bile salts are converted to acids on an Amberlyst A-15 column and are separated into
Ronald O Ball et al.
The Journal of nutrition, 136(6 Suppl), 1682S-1693S (2006-05-17)
Sulfur amino acid metabolism has been receiving increased attention because of the link to chronic diseases such as cardiovascular disease, Alzheimer's disease, and diabetes. In addition, the role of cysteine and optimal intakes for physiological substrates such as glutathione are
Andor W J M Glaudemans et al.
European journal of nuclear medicine and molecular imaging, 40(4), 615-635 (2012-12-13)
(11)C-methionine (MET) is the most popular amino acid tracer used in PET imaging of brain tumours. Because of its characteristics, MET PET provides a high detection rate of brain tumours and good lesion delineation. This review focuses on the role
Olga Z Karicheva et al.
Nucleic acids research, 39(18), 8173-8186 (2011-07-05)
Mutations in human mitochondrial DNA are often associated with incurable human neuromuscular diseases. Among these mutations, an important number have been identified in tRNA genes, including 29 in the gene MT-TL1 coding for the tRNA(Leu(UUR)). The m.3243A>G mutation was described
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資料

USP HPLC Analysis of L-Methionine on Ascentis® Express OH5

Separation of L-Methionine, Pharmaceutical Secondary Standard; Certified Reference Material

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